Age-Specific Dementia Risk Scores Developed for Mid, Late Life
Elevated systolic BP and diabetes mellitus most important vascular risk factors for increased 10-year incident dementia risk at age 55
Increased Flexibility Seen in Preapproval Evidence for New Drugs
Twenty-eight percent of trials used historical, external, or other control; nearly half used surrogate measure as a primary end point
Sleep Problems Not a Major Issue in Rheumatoid Arthritis
Existing sleep problems related mainly to disease-related measures, such as pain and reduced function, more so than disease duration
Choroid Plexus Volume Up With Advanced Cognitive Impairment
Larger volume associated with severity of cognitive impairment across Alzheimer disease spectrum
Cessation Program in Cancer Clinics May Reach More Tobacco Smokers
Low-burden, point-of-care program may increase access to and impact of treatment to assist tobacco cessation
Responses to Screening for Suicide Risk May Differ for Gun Owners
When probability of suicide attempt increases, gun owners may be less likely to endorse survey items about passive, active suicidal ideation
During Pandemic, Growth of Clinicians With X-Waivers for Buprenorphine Prescribing Slowed
Survey of 126 clinicians helps pinpoint barriers to obtaining waivers, prescribing buprenorphine
Self-Reported Postpartum Depressive Symptoms Up During Pandemic
States with greater increases in symptoms had fewer deaths from COVID-19 and lower women's unemployment rates
Buprenorphine Underused for OUD, Particularly Polysubstance Use
Yet, study shows buprenorphine is effective in protecting against overdose in this population
Serotonergic Antidepressants in Pregnancy Not Tied to Neonatal Seizures
Maternal use of SSRIs, SNRIs in first trimester of pregnancy not linked to increased risk for neonatal seizures or childhood epilepsy in offspring