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Pioglitazone Use Linked to Reduced Dementia Risk in T2DM

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Reduction in risk was greatest for those with history of ischemic heart disease or stroke

Prior Paid Medical Malpractice Claims Predict Future Claims Risk

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Findings independent of whether a physician is practicing in a high- or low-risk specialty

Drugs With Low Clinical Benefit Show Higher Direct-to-Consumer Spending

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Majority of the top-selling prescription drugs sold in 2020 were rated as offering low added benefit

FDA Panel Considers Making Opioid Overdose Antidote More Easily Obtainable

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Naloxone nasal spray can already be obtained without a prescription, but currently, buyers must get it from a pharmacist

Many COVID-19 Hospital Survivors Face Adverse Effects at Six Months

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Cardiopulmonary symptoms, financial and functional problems seen six months after COVID-19-related discharge

10 Percent of New Drugs Approved Without Meeting Primary Efficacy End Points

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Findings seen for 21 drug approvals between 2018 and 2021, with only one-third needing postmarketing studies

Data Show Big Drop in Number of Americans in Medical Debt

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Number of Americans with medical debt on their credit reports fell by 8.2 million from 2020 to 2022

Initiation of Opioids Not Recommended for Chronic Pain

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Strong recommendation made against long-term opioid therapy, especially for younger age groups, those with substance use disorder

Practicing Physicians Saw Excess Mortality During COVID-19 Pandemic

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However, physicians had substantially lower excess mortality than the general U.S. population

Early-Life Adversity Tied to Poor Mental Health, Cognition in Later Childhood

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Specific impacts seen on working memory and vocabulary