Pioglitazone Use Linked to Reduced Dementia Risk in T2DM
Reduction in risk was greatest for those with history of ischemic heart disease or stroke
Prior Paid Medical Malpractice Claims Predict Future Claims Risk
Findings independent of whether a physician is practicing in a high- or low-risk specialty
Drugs With Low Clinical Benefit Show Higher Direct-to-Consumer Spending
Majority of the top-selling prescription drugs sold in 2020 were rated as offering low added benefit
FDA Panel Considers Making Opioid Overdose Antidote More Easily Obtainable
Naloxone nasal spray can already be obtained without a prescription, but currently, buyers must get it from a pharmacist
Many COVID-19 Hospital Survivors Face Adverse Effects at Six Months
Cardiopulmonary symptoms, financial and functional problems seen six months after COVID-19-related discharge
10 Percent of New Drugs Approved Without Meeting Primary Efficacy End Points
Findings seen for 21 drug approvals between 2018 and 2021, with only one-third needing postmarketing studies
Data Show Big Drop in Number of Americans in Medical Debt
Number of Americans with medical debt on their credit reports fell by 8.2 million from 2020 to 2022
Initiation of Opioids Not Recommended for Chronic Pain
Strong recommendation made against long-term opioid therapy, especially for younger age groups, those with substance use disorder
Practicing Physicians Saw Excess Mortality During COVID-19 Pandemic
However, physicians had substantially lower excess mortality than the general U.S. population
Early-Life Adversity Tied to Poor Mental Health, Cognition in Later Childhood
Specific impacts seen on working memory and vocabulary