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Valproic acid and topiramate are confirmed teratogens

Study Confirms Teratogenicity of Valproic Acid, Topiramate

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Eight specific types of major congenital malformations associated with prenatal exposure to valproic acid
Metagenomic next-generation sequencing of cerebrospinal fluid obtained from patients with meningitis or encephalitis can improve diagnosis of neurologic infections

Next-Gen Sequencing of CSF Improves Diagnosis of CNS Infections

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Eight of 13 diagnoses made solely by metagenomic NGS had likely clinical effect, seven guided treatment
Engaging in higher levels of physical activity in childhood is associated with better cardiovascular health indicators

Higher Levels of Exercise in Childhood Improve Heart Health

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Better cardiovascular health indicators seen with engaging in higher levels of physical activity
Undervaccinated and unvaccinated children are at increased risk for pertussis

Pertussis Risk Up for Undervaccinated, Unvaccinated Children

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However, most pertussis cases occur among vaccinated children further away from last DTaP dose
Children with community-acquired pneumonia often receive diagnostic testing and antibiotic therapy despite publication of guidelines against their routine use in 2011

Diagnostic Testing, Antibiotics Overused in Pediatric CAP

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Chest radiography ordered in 43 percent, antibiotics prescribed in 73.9 percent of community-acquired pneumonia visits
The U.S. Preventive Services Task Force recommends preexposure prophylaxis and HIV screening for prevention of HIV infection. These recommendations form the basis of two final recommendation statements published online June 11 in the Journal of the American Medical Association.

USPSTF Issues Recommendations on HIV Screening, Prevention

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Recommendations support PrEP for those at high HIV risk, screening for teens, adults, in pregnancy
There is variability in data relating to the safety of lithium during breastfeeding

Data Insufficient for Safety of Lithium During Breastfeeding

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Lithium transfer to infants is variable; three cases of adverse effects reported, but confounding occurred
The IB-Stim has received marketing approval from the U.S. Food and Drug Administration as the first medical device used to help alleviate functional abdominal pain in 11- to 18-year-old patients with irritable bowel syndrome

Marketing OK’d for Device to Help Reduce IBS Symptoms in Adolescents

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IB-Stim helps to reduce abdominal pain in 11- to 18-year-olds with irritable bowel syndrome
Health care has modest effects on extending life expectancy in the United States

Access to Health Care Has Little Impact on Longevity

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Social, behavioral factors account for greater portion of premature mortality than does health care
Pregnancy hyperglycemia at levels below the threshold for gestational diabetes mellitus and maternal obesity are associated with childhood obesity

Hyperglycemia in Pregnancy May Up Risk for Obesity in Offspring

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Children of obese women with gestational diabetes have increased risk for childhood obesity