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The gene KLF14 is associated with the risk of developing type 2 diabetes and appears to regulate hundreds of other genes active in fat cells

New Clues to How KLF14 Gene Affects Women’s Diabetes Risk

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Researchers found variants determine where body fat is stored, regulation of fat cells
In obstructive sleep apnea

Nocturnal Hypoxemia Severity Linked to Renal RAS Activity

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In OSA, severity of nocturnal hypoxemia influences renal, not systemic RAS activation
For patients with inflammatory bowel disease

Low Hep B Vaccine Response Rate Linked to IBD Treatment

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Treatment with infliximab and/or azathioprine associated with weaker response to vaccination
In Australia

Cancers Differ in Indigenous, Non-Indigenous Populations

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Generally, indigenous cancer rates lower, except for lung cancer in men, cervical in women
Results of in vitro fertilization cycles using eggs from older donors are as good as those using eggs from younger women

ASRM: Good Results From IVF Egg Donors Over Age 35

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Pregnancy, live birth rates from older and younger women appear comparable
Hypofractionated radiation therapy with incorporated boost over a shorter period of time treats early-stage breast cancer as well as longer

ASTRO: Shorter Radiation OK for Early Breast Cancers

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High-dose therapy shows same survival rates as longer course of standard radiation
Cardiac surgery patients given blood stored for more than six weeks face no greater harm than those who get blood donated within two weeks

Older Blood Appears Safe for Cardiac Surgery Patients

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Storage duration doesn't affect complications, mortality rate
For patients undergoing total knee arthroplasty and total hip arthroplasty for osteoarthritis

Knee, Hip Arthroplasty Tied to Increased Short-Term MI Risk

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Increased risk of myocardial infarction in first post-op month; but not during overall follow-up
For patients with colorectal cancer

SNORA42 Identified as Novel Oncogene in Colorectal Cancer

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Increased SNORA42 expression is independent prognostic factor for overall, disease-free survival
A previously unrecognized hypothalamic-sympathetic nervous system-renal axis has been identified that may impact glucose homeostasis

Hypothalamic Axis Ups Glucose Tolerance Via Glycosuria

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Hypothalamic-sympathetic nervous system-renal axis ID'd that regulates tubular glucose reabsorption