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For patients with non-small-cell lung cancer

Age at NSCLC Diagnosis Tied to Odds of Targetable Phenotype

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Younger age at diagnosis linked to increased frequency of targetable phenotype
More than half of U.S. states are poorly prepared to respond to infectious disease outbreaks

Over Half of U.S. States Ill Prepared for Disease Outbreaks

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Efforts needed to boost ability to respond to viruses, superbug threats
People with darker skin are about one-third more likely to have acral pigmented lesions on their palms and soles

Acral Pigmented Lesions More Common on Darker Skin

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Authors hope findings raise awareness, increase dermoscopy for those at risk
A case of cryptococcal meningitis with false-negative cerebrospinal fluid culture results following receipt of capecitabine has been described in a case report published in the December issue of the Journal of Clinical Pharmacy and Therapeutics.

Antineoplastic Agent Obscures Diagnosis of Fungal Meningitis

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Cerebrospinal fluid culture results were negative following receipt of capecitabine
The efficacy of ovarian cancer screening is unclear

Longer Follow-Up Needed to Evaluate Ovarian CA Screening

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Significant reduction in mortality with multimodal screening when prevalent cases excluded
Activation of c-Jun N-terminal kinase is essential for herpes simplex virus gene expression during virus reactivation from latent neuronal infection

c-Jun N-terminal Kinase Essential for HSV Reactivation

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JNK signaling results in histone methyl-phospho switch on HSV lytic promoters
For individual patients with poorly-controlled asthma

Nasal, Pharyngeal EPX Levels Linked to Sputum Eosinophilia

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Strong correlation seen for eosinophil peroxidase levels in adults with poorly-controlled asthma
For adult patients with refractory Crohn's disease with impaired quality of life

HSCT Not Linked to Sustained Remission in Refractory Crohn’s

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More patients undergoing HSCT able to discontinue treatment for at least three months
Stroke risk appears to more than double in the first week following a shingles diagnosis

Risk of CV Events Up After Shingles Diagnosis in Seniors

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Chance of stroke, myocardial infarction increased most in the first week after diagnosis
There's been a sharp rise in the number of industry-funded clinical trials and a significant decline in those financed by the U.S. government in recent years

Industry Outpacing NIH in Funding Research

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Analysis finds studies paid for by private sector increasing, while U.S.-sponsored trials decline