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Having an identical twin diagnosed with cancer increases the other twin's risk of developing not just that type but any form of cancer

Researchers Calculate Family Risk Estimates for Cancer

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Estimated 33 percent of overall risk is genetic; certain types of cancer have additional risk
For women with breast cancer treated with primary systemic chemotherapy

Axillary pCR Linked to Improved Breast Cancer Survival

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Very high survival for axillary pathologic complete response for women with HER2-positive disease
A case report published online Jan. 4 in JAMA Neurology highlights a neuropsychological test profile conducted on a patient with chronic traumatic encephalopathy.

Signs of CTE in Brain of Deceased 25-Year-Old Football Player

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Neuropsychological profile conducted prior to death of patient who had played football from age 6
Initial diagnostic characteristics may be able to identify men initiating active surveillance who could avoid confirmatory biopsy

Diagnostic Factors May Help Patients Avoid Prostate Biopsy

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Prostate-specific antigen density, total tumor length are significant predictors
β-genus human papillomavirus is a risk factor for cutaneous squamous cell carcinoma in otherwise healthy individuals

β-Genus Human Papillomavirus Poses Skin Cancer Risk

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HPV subtypes 5, 8, 17, 20, and 38 tied to significant increased risk
For patients with non-small-cell lung cancer with activating epidermal growth factor receptor mutations

Support for First-Line Erlotinib in NSCLC With EGFR Mutations

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And erlotinib therapy beyond progression may delay salvage tx for some patients

December 2015 Briefing – Pathology

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Here are what the editors at HealthDay consider to be the most important developments in Pathology for December 2015. This roundup includes the latest...
Third-trimester screening for alloimmunization in Rhesus c-negative women improves detection and treatment of hemolytic disease of the fetus and newborn

Third-Trimester Screen Detects Late Alloimmunization

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Detection through additional screening facilitates timely treatment
Higher secretion rates of secretory immunoglobulin A are associated with decreased risk of cancer death

Secretory IgA Secretion Rate Linked to Risk of Cancer Death

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Lower risk of non-lung cancer deaths observed with increased sIgA secretion rate
For patients receiving antimicrobial injections targeting methicillin-resistant Staphylococcus aureus

Antimicrobial Stewardship Improves Outcomes for MRSA

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Daily review of prescriptions linked to reduction in time to administer effective antimicrobials