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A new blood test might improve doctors' ability to track the spread of advanced melanoma

New Blood Test May Improve Tracking of Advanced Melanoma

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Test monitors blood levels of DNA fragments from dead cancer cells
Imatinib (Gleevec) blocks CDK5-mediated peroxisome proliferator-activated receptor γ phosphorylation as an antagonist ligand

PPARγ Antagonist Imatinib Improves Insulin Sensitivity

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Imatinib improves insulin sensitivity without causing side effects seen with other PPARγ-targeting drugs
Use of bone marrow as the stem cell source for hematopoietic stem cell transplantation increases with increasing incomes

Stem Cell Sources Used for HSCT Vary by Country, Resources

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Use of bone marrow most common in Americas, Europe; increases with increasing income
There is variability in radiation-induced breast cancer incidence and mortality associated with digital mammography screening

Incidence of Radiation-Induced Breast Cancer Examined

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Women with large breasts projected to have increased risk of radiation-induced breast cancer
Acute ozone exposure increases stress hormones and causes alterations in peripheral lipid metabolism in humans

Acute Ozone Exposure Ups Stress Hormone in Humans

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Increased stress hormones, alterations in lipid metabolites are similar to changes seen in rodents
Allergic rhinitis constitutes a considerable burden

Allergic Rhinitis Constitutes Considerable Burden

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Patients with prevalent AR more likely to develop asthma, mental health comorbidities
Nivolumab in combination with contact immunotherapy can successfully treat in-transit melanoma

Nivolumab, Contact Immunotx Treats In-Transit Melanoma

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Two cases illustrate successful tx with nivolumab in combination with contact immunotherapy
For women undergoing digital mammography screening

False-Positive Mammography Results Are Common

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Highest rates of false-positive results and additional imaging seen for women aged 40 to 49 years
Three newly identified genes associated with primary open angle glaucoma bring the total number of such genes to 15

Researchers ID Three New Glaucoma-Related Genes

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Variations in FOXC1, TXNRD2, and ATXN2 associated with primary open angle glaucoma
Even a slight decline in kidney function can potentially lead to heart damage

Even Small Decline in Kidney Function Tied to CVD Risk

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Associated with an increase in the mass of the left ventricle