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A case of acquired syphilis leading to involvement of the bone marrow and liver is described in a report published online March 22 in the Annals of Internal Medicine.

Report of Bone Marrow/Liver Pathology Caused by Syphilis

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Case study describes 65-year-old patient with late-latent syphilis with normocytic anemia
Proprotein convertase subtilisin/kexin type 9 monoclonal antibodies may represent a promising treatment option for acute coronary syndrome

PCSK9 Monoclonal Antibodies Show Promise in ACS

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Suggestion of dual antidyslipidemic and plaque-stabilizing effects in the early phase of ACS
In apparent uterine-confined endometrial cancer

Marker IDs More Lymph Node Mets in Endometrial Cancer

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Addition of ICG and near-infrared imaging ups detection of SLN, LN metastases
Among U.S. high school athletes

Wrestling Wins for Most High School Athletic Skin Infections

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Overall rate of skin infections is 2.27 per 100,000 athlete exposures; mostly bacterial and tinea
In a case report published online March 17 in JAMA Ophthalmology

Endogenous Endophthalmitis ID’d After Breast Implant Surgery

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Case report describes endophthalmitis with chorioretinal involvement caused by Candida albicans
Patients with maturity-onset diabetes of the young 1 (MODY1) are often misdiagnosed as having type 2 diabetes

MODY1 Form of Diabetes May Require Alternate Treatment

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Mutations in HNFα cause Mature-Onset Diabetes of the Young 1, with diminished GSIS
Interpretation of a single breast biopsy slide per case predicts low likelihood of verification for diagnosis of atypia or ductal carcinoma in situ

Low Likelihood for Atypia, DCIS Verification With Single Slide

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Highly probable verification for invasive breast cancer and benign without atypia diagnoses
For patients with hypertrophic cardiomyopathy

Genotype Doesn’t Predict A-Fib in Hypertrophic Cardiomyopathy

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Genotype was not predictive of onset or severity of atrial fibrillation
A novel mechanism has been proposed for the role of exercise in mitigating the detrimental impact of a fast-food diet in mice

Exercise Prevents Diet-Induced Cell Senescence in Adipose Tissue

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In experimental study, prevents senescent cell accumulation, phenotype expression
A genetic test of homologous recombination genes might help predict outcomes for women diagnosed with ovarian cancer

Gene Panel Test May Help Predict Ovarian Cancer Prognosis

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Women with mutations in some 'DNA repair' genes may survive much longer, research shows