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Acneiform eruptions due to the BRAF kinase inhibitor vemurafenib in a patient with multiple metastatic melanoma lesions are described in a case report published online Aug. 11 in the Journal of Dermatology.

Acneiform Eruptions Observed After Vemurafenib Treatment

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Case report describes acneiform eruptions after tx of metastatic melanoma lesions with vemurafenib
For HIV-infected adults

Major Depressive Disorder Ups Acute MI Risk in HIV-Infected

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HIV-infected adults with major depressive disorder have ~30 percent increased risk for AMI
Deaths from overdoses of illicitly manufactured fentanyl (IMF) have increased significantly in recent years

CDC: Synthetic Fentanyl a Major Factor in Opioid Overdose Deaths

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Number of synthetic opioid-involved overdose deaths rose 79 percent in 27 states from 2013 to 2014
U.S. health officials report that the Zika virus can be spread sexually even when a partner shows no signs of infection. The research was published in the Aug. 26 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

CDC: Zika Transmitted by Sex Partner With No Symptoms

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Second report highlights ties between Zika and Guillain-Barré syndrome
A common genetic variation significantly increases the odds of asthma in children who've had a severe respiratory illness at a young age

Bronchiolitis Plus Gene Variant Raises Asthma Risk in Children

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Higher risk seen in those with PAI-1 gene variant and serious respiratory infection at a young age
In the future

Circulating Biomarkers May Be Indicative of Stroke Risk

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High levels of CRP, tHcy, TNFR2, and VEGF indicate significantly higher odds for incident ischemic stroke
Early exposure to diabetes mellitus or higher insulin resistance has an adverse effect on left ventricular remodeling and function

Diabetes, Insulin Resistance Adversely Affect LV Function

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Early diabetes group has less favorable LV mass, LV ejection fraction
Children aged 8 to 11 weeks have an increased rate of intussusception hospitalization after introduction of rotavirus vaccine

Intussusception Hospitalization Rate Up at Age 8 to 11 Weeks

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No consistent change among all children aged <12 months after introduction of rotavirus vaccine
Excess weight is linked to risk of developing at least eight types of cancer

IARC: Absence of Excess Body Fat Lowers Risk of Many Cancers

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International committee finds slimmer individuals less likely to develop variety of malignancies
Obese women have significantly greater total vitamin D stores than normal-weight women

Obese Women Have Greater Adipose Stores of Vitamin D

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Distribution of vitamin D between subcutaneous, omental adipose tissue similar for obese, non-obese