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There is a graded association between intensity of statin therapy and mortality for patients with established atherosclerotic cardiovascular disease

High-Intensity Statins Tied to Better Survival in CVD Patients

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Significant survival advantage compared with moderate-intensity statins, even among older adults
An experimental Zika vaccine shows promise

DNA-Based Zika Vaccine Shows Protection Against Infection

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Results from animal study encouraging and human trials are underway
Serum 25-hydroxyvitamin D levels may affect breast cancer patients' chances of survival

Higher Serum Vitamin D Levels Up Survival in Breast Cancer

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Link is strongest in premenopausal women, researchers say
In a report published online Nov. 8 in Pediatrics

Report of Recurrent Immune Thrombocytopenia After Flu Shot

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Case report describes 4.5-year-old with three admissions for ITP, each within a week of vaccine
Macrophage cyclooxygenase-2 deletion is associated with progression of diabetic nephropathy

Macrophage COX-2 Prevents Diabetic Nephropathy Progression

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Mice with COX-2 deletion in hematopoietic cells or macrophages have severe DN vs WT diabetic mice
Increased body mass index may have a moderate effect on hand arthritis

Meta-Analysis Links Increased BMI, Hand Osteoarthritis

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Weak but significant effect seen on risk of radiographic hand osteoarthritis
Patients with type 1 diabetes diagnosed at age 15 to 27 years have low cumulative incidence of end-stage renal disease and increased mortality during long-term follow-up

Cumulative Incidence of ESRD Low in Patients With Type 1 DM

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Cumulative incidence of ESRD 4.6 percent during 30 years' follow-up for those diagnosed at age 15 to 27
Genetic variations correlate with mortality in the elderly

Genetic Mortality Risk Can Be Attenuated by Lifestyle

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Mortality up to 64 percent lower for those with low-risk lifestyle profile, independent of genetic risk
An adapted clinical practice guideline

Guideline Adapted for Surgical Antimicrobial Prophylaxis

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ADAPTE methodology was used to produce an adapted clinical practice guideline for SAP
BACH2 is a major risk locus for Addison's disease

BACH2 Identified As Risk Locus for Addison’s Disease

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Extended exome capture array shows BACH2 correlates with Addison's disease development