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Mutant BCL11B has been identified as a cause of severe combined immunodeficiency in newborn screening

Newborn Screen IDs Previously Unknown Cause of SCID

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Identification of missense mutation in BCL11B; immune deficit in infant corrected with HSCT
Outreach programs can increase hepatocellular carcinoma screening rates among patients with documented or suspected cirrhosis

Outreach Strategies Can Up HCC Screening in Cirrhosis

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More patients undergo screening when they receive mailed invitations for screening examination
Hematopoietic cell transplantation cancer survivors have increased risk of late morbidity and mortality

Morbidity, Mortality Up for HCT Cancer Survivors

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Late morbidity and mortality among cancer survivors with hematopoietic cell transplantation
Smoking is associated with an increased risk of acute ST-segment elevation myocardial infarction

Highest Increase in Acute STEMI Risk for Youngest Smokers

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Risk up with smoking; more than eight-fold increase in acute STEMI risk for those aged <50 years
Statins seem not to be associated with the risk of colorectal adenoma

Meta-Analysis: Statins Cut Risk of Advanced Colorectal Adenoma

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In meta-analysis, statin use linked to reduced risk of advanced, but not any colorectal adenoma
A gene mutation has been identified that could be associated with early-onset Parkinson's disease

Gene Mutation Linked to Early-Onset Parkinson’s Disease

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Mutated GCH1 gene tied to 23 percent increased risk of Parkinson's; symptoms five years earlier
The first case of an infant who developed glaucoma after being exposed to the Zika virus while in the womb has been reported by an international team of researchers. The case was reported online Nov. 30 in Ophthalmology.

Infant Diagnosed With First Case of Zika-Related Glaucoma

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Brazilian baby developed condition after being exposed to virus in womb
Methylation of a gene panel is a strong predictor of survival outcomes in metastatic breast cancer

Methylation of Gene Panel May Help Predict Breast CA Survival

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High cumulative methylation index linked to shorter median progression-free, overall survival
For patients hospitalized with acute decompensated heart failure

Review Links Natriuretic Peptide Thresholds to Mortality in ADHF

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Achieving NP predischarge thresholds cuts mortality, readmission in acute decompensated heart failure
The 2011 clinical practice guideline on urinary tract infection in young children has been reaffirmed

Clinical Practice Guideline on UTI in Febrile Young Reaffirmed

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2011 CPG on urinary tract infection in infants and young children reaffirmed after review of literature