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The novel herpes simplex virus (HSV) helicase-primase inhibitor pritelivir is more effective than valacyclovir for reducing genital HSV-2 shedding

Pritelivir Beats Valacyclovir for Genital HSV-2 Shedding

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Phase 2 trial shows decline in relative risk of herpes simplex virus shedding over 28 days
There are about 6

Incidence of Nontyphoidal Salmonella Infections Estimated

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Incidence estimated at about 6,200 resistant culture-confirmed infections per year
Pathologists have wide variability in treatment suggestions for melanocytic lesions

Pathologists Vary in Suggested Therapy for Melanocytic Lesions

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Variation may lead to undertreatment or overtreatment of melanocytic lesions
Health care provider burnout is negatively associated with quality and safety of health care

Health Care Provider Burnout Negatively Affects Quality, Safety

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Health care provider burnout negatively linked to quality and safety of health care
MicroRNAs (miR-203 and miR-205) could be useful prognostic markers in cutaneous squamous cell carcinoma

MicroRNAs 203 and 205 Are Prognostic in Cutaneous SCC

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miR-205 expression in tumors with pathologic features indicating poor prognosis, in invasion front
The U.S. Preventive Services Task Force recommends against routine serologic screening for genital herpes simplex virus infection in asymptomatic adolescents and adults

USPSTF Recommends Against Routine HSV Screening

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High proportion of false-positive results and associated psychological harms with screening
Drug overdose deaths increased 23 percent between 2010 and 2014

CDC: Fatal Drug Overdoses Up Significantly in the United States

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Prescription opioids and heroin lead the increase, latest government data show
For patients with type 2 diabetes mellitus

Long-Term DPP4-Inhibitor Use Not Tied to Fracture Risk in T2DM

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No increase in risk of any fracture, osteoporotic or hip fractures with continuous long-term use
In older adults

Dysglycemia Affects Brain Structure, Cognition in Seniors

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Brain infarcts, white matter hyperintensities volume up; total white matter down
Cervicovaginal secretions from pregnant and nonpregnant women contain HIV infectivity-linked immune mediators

Cervicovaginal Secretions Contain HIV-Linked Immune Mediators

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No difference in infectivity for pregnant and nonpregnant women