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Serum levels of seven modified metabolites are associated with renal function decline and time to end-stage renal disease among patients with type 1 diabetes

Metabolites Linked to Renal Decline, Time to ESRD in T1DM

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Findings in patients with type 1 diabetes, proteinuria, and chronic kidney disease stage 3
Developing hypertension in very old age may provide some protection from dementia

Hypertension Onset After Age 80 May Protect Against Dementia

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Association independent of antihypertensive medication use
In a clinical practice guideline published online Jan. 16 in the Journal of Clinical Oncology

Recommendations Developed for Small Renal Mass Management

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Data from 83 studies used to develop guideline for management of patients with small renal masses
Just 20 minutes of moderate exercise may reduce inflammation in the body

Brief Bouts of Exercise Can Reduce Inflammation

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20 minutes on a treadmill linked to drop in immune cells tied to inflammation
The interaction between antibiotics and human growth and obesity is explored in a historical perspective piece published in the Jan. 17 issue of the Annals of Internal Medicine.

Interaction Between Antibiotics, Obesity Is Complex

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Since the 2000s, attention has turned toward understanding role of abx, microbiome in obesity
Vulvar and vaginal melanomas have unique molecular features as compared to nongynecologic melanoma

Unique Molecular Features for Vulvar, Vaginal Melanomas

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BRAF most frequently mutated gene in VVMs, while NRAS mutations are rarely seen
Carbapenem-resistant Enterobacteriaceae is more widespread in U.S. hospitals than previously thought and needs to be more closely monitored

Carbapenem-Resistant Bacteria More Problematic Than Thought

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Study of four U.S. hospitals found wide variety of species resistant to antibiotics of last resort
Men who have sex with men receiving antiretroviral therapy to treat HIV infection may be at increased risk for syphilis

Syphilis Risk May Be Higher in HIV Patients on Antiretrovirals

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Medications may raise susceptibility to bacterium that causes the sexually transmitted disease
Many doctors bill their private-paying patients two

Physician Excess Charges Create Financial Burden for Patients

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Fees affect uninsured Americans, privately insured patients who use out-of-network physicians
For patients with acute decompensated heart failure

BNP, Gal-3 Levels Predict 60-Day Readmission in Heart Failure

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Addition of Gal-3 to BNP significantly improves prediction in acute decompensated heart failure