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January 2017 Briefing – Pathology

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Here are what the editors at HealthDay consider to be the most important developments in Pathology for January 2017. This roundup includes the latest...
For patients with ulcerative colitis

Relapse Risk Up With Low Vitamin D Levels in Ulcerative Colitis

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Remission vitamin D level of ≤35 ng/mL linked to increased risk of clinical relapse
A breath test to detect esophageal and gastric cancers shows promise

Breath Test to Detect Esophageal, Gastric Cancers May Be Feasible

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Test could reduce the number of unnecessary endoscopies, researcher says
Developing or worsening type 2 diabetes could be an early sign of pancreatic cancer

New or Worsening T2DM Could Indicate Pancreatic Cancer

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Type 2 diabetes could be the first sign of hidden pancreatic cancer, researchers say
Programmed cell death 1 expression is associated with chronic rhinosinusitis with nasal polyps disease severity

PD-1 Expression Tied to Chronic Rhinosinusitis With Nasal Polyps

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Higher PD-1 expression in CRSwNP vs nasal tissue from controls; PD-1, IL-5 mRNA expression linked
For patients with atrial fibrillation

TGF-β1 Linked to Recurrent A-Fib After Catheter Ablation

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Patients with paroxysmal atrial fibrillation have highest levels of transforming growth factor-β1
Bone marrow-derived mesenchymal stem cell-derived exosomes promote retinal ganglion cell survival

BMSC-Derived Exosomes Promote Retinal Ganglion Cell Survival

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Significant neuroprotective, neuritogenic effects with BMSC-exosome treatment of primary retinal cultures
HIV-infected adults have diabetes mellitus prevalence of 10.3 percent

Diabetes Mellitus Prevalence Higher in HIV-Infected Adults

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Increased prevalence in HIV-infected subgroups, including women, those aged 20 to 44, non-obese
For adult patients undergoing hematopoietic cell transplantation

Pre-Transplant Depression May Impair Post-HCT Outcomes

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Pre-transplant depression tied to lower overall survival, higher risk of acute GVHD in allogeneic HCT
Hypoglycemia can promote mobilization of specific subsets of leukocytes and induce pro-inflammatory functional changes in immune cells

Hypoglycemia Induces Pro-Inflammatory Functional Changes

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Increases numbers of leukocytes in healthy controls, patients with normal awareness of hypoglycemia