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The prescription drug abuse epidemic in the United States might be associated with a higher mortality rate than has been reported previously

CDC: Opioid-Related Mortality Rate Might Be Underestimated

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Death certificates from drug-linked infections may not label opioids as possible cause
Chromosome instability within lung cancer tumors increases the risk of recurrence or death and may help forecast recurrence long before standard tests

Chromosome Instability Test Prognostic in NSCLC

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Chromosome instability associated with higher risk of relapse, death within 2 years
A blood-based genome testing service provides accurate results within 72 hours

Blood-Based Genome Testing Feasible for Rapid Mutation Assay

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Mutation results available within 72 hours for 94 percent of non-small-cell lung CA samples evaluated
Exposure of the sinonasal airway barrier to chronic airborne particulate matter has destructive effects

Pollution Linked to Destructive Effect on Upper Sinonasal Airway

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Destructive effect of chronic airborne PM in mice includes pro-inflammatory cytokine release
The bacterial cell wall-derived muramyl dipeptide postbiotic lowers adipose inflammation and reduces glucose intolerance in obese mice

Postbiotic Could Lower Glucose, Inflammation in Obesity

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MDP postbiotic linked to reduction in hepatic insulin resistance during obesity, low-level endotoxemia

T2DM Risk Cut by Variant in Sulfonylurea Receptor Encoder

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Missense variant in ABCC8 gene also linked to reduced risk of coronary heart disease
Hepatitis B virus reactivation is a safety concern for patients with HBV and hepatitis C virus coinfection receiving direct-acting antiviral agents

HBV Reactivation Is Concern With DAA Tx in HBV-HCV Coinfection

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29 cases of HBV reactivation reported in patients with coinfection receiving direct-acting antivirals
The incidence of sudden unexpected death in epilepsy (SUDEP) is 0.22 per 1

AAN: SUDEP Incidence 1 in 4,500 Children, 1 in 1,000 Adults/Year

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Major risk factor for sudden unexpected death in epilepsy is generalized tonic-clonic seizures
Peak postoperative high-sensitivity troponin T is associated with increased risk of 30-day mortality among patients undergoing noncardiac surgery

Post-Op hsTnT Linked to 30-Day Mortality After Noncardiac Sx

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Increased risk of 30-day mortality for absolute high-sensitivity troponin T change of 5ng/L or higher
Only a few select incidental thyroid nodules require further evaluation

Only Select Incidental Thyroid Nodules Need Further Evaluation

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Indiscriminate workup of incidental thyroid nodules with ultrasonography is potentially harmful