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Chromosome instability within lung cancer tumors increases the risk of recurrence or death and may help forecast recurrence long before standard tests

Chromosome Instability Test Prognostic in NSCLC

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Chromosome instability associated with higher risk of relapse, death within 2 years
A blood-based genome testing service provides accurate results within 72 hours

Blood-Based Genome Testing Feasible for Rapid Mutation Assay

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Mutation results available within 72 hours for 94 percent of non-small-cell lung CA samples evaluated
Exposure of the sinonasal airway barrier to chronic airborne particulate matter has destructive effects

Pollution Linked to Destructive Effect on Upper Sinonasal Airway

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Destructive effect of chronic airborne PM in mice includes pro-inflammatory cytokine release
The bacterial cell wall-derived muramyl dipeptide postbiotic lowers adipose inflammation and reduces glucose intolerance in obese mice

Postbiotic Could Lower Glucose, Inflammation in Obesity

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MDP postbiotic linked to reduction in hepatic insulin resistance during obesity, low-level endotoxemia

T2DM Risk Cut by Variant in Sulfonylurea Receptor Encoder

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Missense variant in ABCC8 gene also linked to reduced risk of coronary heart disease
Hepatitis B virus reactivation is a safety concern for patients with HBV and hepatitis C virus coinfection receiving direct-acting antiviral agents

HBV Reactivation Is Concern With DAA Tx in HBV-HCV Coinfection

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29 cases of HBV reactivation reported in patients with coinfection receiving direct-acting antivirals
The incidence of sudden unexpected death in epilepsy (SUDEP) is 0.22 per 1

AAN: SUDEP Incidence 1 in 4,500 Children, 1 in 1,000 Adults/Year

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Major risk factor for sudden unexpected death in epilepsy is generalized tonic-clonic seizures
Peak postoperative high-sensitivity troponin T is associated with increased risk of 30-day mortality among patients undergoing noncardiac surgery

Post-Op hsTnT Linked to 30-Day Mortality After Noncardiac Sx

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Increased risk of 30-day mortality for absolute high-sensitivity troponin T change of 5ng/L or higher
Only a few select incidental thyroid nodules require further evaluation

Only Select Incidental Thyroid Nodules Need Further Evaluation

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Indiscriminate workup of incidental thyroid nodules with ultrasonography is potentially harmful
Black men appear to have a higher incidence of preclinical prostate cancer and a higher risk of metastatic progression than the general population

Black Men Have Higher Rate of Preclinical Prostate Cancer

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Also increased risk of progression to metastatic disease compared with the general population