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A validated 31-gene expression profile signature improves identification of patients with melanoma at high risk of metastasis when used in combination with the American Joint Committee on Cancer outcome prediction tool

Gene Expression Profile Improves ID of High-Risk Melanoma

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Findings based on use of 31-gene profile along with an online survival prediction tool
A genetic variant that is associated with both multiple sclerosis and systemic lupus erythematosus has been identified

Genetic Variant Tied to MS and Systemic Lupus Identified

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However, BAFF variant was likely selected over time as an adaptive response to malaria
Early treatment of rheumatoid arthritis (RA) is important for long-term outcomes

Early RA Treatment Important for Long-Term Outcomes

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Other study shows drop in mortality attributable to rheumatoid arthritis from 1987 to 2011
Many children with a blood lead level ≥10 µg/dL are being missed by pediatric care providers

Pediatricians Missing Elevated Blood Lead Levels in U.S.

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In 23 of 39 reporting states, pediatric care providers identified fewer than half of children with EBLL
Physician burnout factors include control

Risk Factors in Six Areas Tied to Physician Burnout

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Tool gauging burnout focuses on workload, control, rewards, community, fairness, values
A proposal to replace private insurance with government-funded health care for all moved forward in California on Wednesday as Democrats on the Senate Health Committee voted to advance the measure.

Single-Payer Health System Bill Moves Forward in California

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Not yet clear where money for the single-payer system would come from
Molecular autopsy for electrical disorder and cardiomyopathy genes identifies a modest but realistic yield in sudden arrhythmic death syndrome

Molecular Autopsy IDs Causes of Sudden Arrhythmic Death

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Researchers identified clinically actionable rare variants in 13 percent of SADS cases
Deep learning with deep convolutional neural networks can result in accurate detection of tuberculosis on chest radiographs

Deep Convolutional Neural Networks Accurately Detect TB

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Ensemble of AlexNet and GoogLeNet was best-performing classifier, with AUC of 0.99
A fatal case of propofol-induced acute necrotizing pancreatitis has been described in a case report published online April 10 in the Journal of Clinical Pharmacy and Therapeutics.

Fatal Case of Suspected Propofol-Induced Pancreatitis Described

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57-year-old woman developed severe abdominal pain with nausea, vomiting after thyroidectomy
The prescription drug abuse epidemic in the United States might be associated with a higher mortality rate than has been reported previously

CDC: Opioid-Related Mortality Rate Might Be Underestimated

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Death certificates from drug-linked infections may not label opioids as possible cause