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Ribociclib is beneficial for pre- and perimenopausal women with hormone receptor-positive

SABCS: Ribociclib Ups PFS in HR+ HER2− Advanced Breast Cancer

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Significant improvement in progression-free survival for pre- and perimenopausal women
Previous findings that systemic use of antibiotics increases the risk of diabetes may actually be explained by clinical and lifestyle factors

Link Between Diabetes, Antibiotic Use Called Into Question

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Clinical, lifestyle factors may have confounded previous findings linking antibiotics, diabetes risk
Lymph node density can help predict outcomes in patients with papillary thyroid cancer

Lymph Node Density Predicts Thyroid Cancer Outcomes

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Papillary thyroid cancer patients with LND >0.19 have worse disease-specific, overall survival
Lipid-associated genetic risk correlates with the risk of abdominal aortic aneurysm

Lipid-Linked Genetic Risk Tied to Abdominal Aortic Aneurysm

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Genetic elevation of LDL-C linked to increased AAA risk; increase for HDL-C linked to lower risk of AAA
About one-quarter of adults with chronic kidney disease of unknown cause or familial nephropathy or hypertension have diagnostic mutations

Diagnostic Mutations ID’d in Chronic Kidney Disease Patients

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Whole-exome sequencing identified diagnostic mutations, including PARN mutations, in two patients
A case of a 16-year-old presenting to the emergency department with acute intermittent porphyria is described in a case report published online Dec. 5 in Pediatrics.

Acute Intermittent Porphyria Described in Teen Girl

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Clinical picture seemed consistent with constipation, but hyponatremia did not fit with diagnosis
CVS Health's planned purchase of insurance giant Aetna

CVS-Aetna Merger Has Implications for Doctors’ Offices

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More health services will likely move out of doctors' offices to store-based providers
Implementation of state newborn screening policies for critical congenital heart disease is associated with a decrease in infant cardiac deaths

State Newborn Screening Policies Cut Infant Cardiac Deaths

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Significant drop in infant cardiac deaths between 2007 and 2013 in states with mandatory screening
Nivolumab treatment for non-small-cell lung cancer may induce successful depletion of HIV reservoir

Nivolumab May Induce Successful Depletion of HIV Reservoir

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Case report describes smoker with HIV infection receiving nivolumab for non-small-cell lung cancer
Oral microbiome composition is associated with the risk of esophageal adenocarcinoma and esophageal squamous cell carcinoma

Oral Microbiome Composition Linked to Esophageal Cancer Risk

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Periodontal pathogen Tannerella forsythia linked to increased risk of esophageal adenocarcinoma