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A new approach to gene therapy can restore immune cell types in infants with newly diagnosed X-linked severe combined immunodeficiency

ASH: New Approach to Gene Tx Restores Immune Cells in X-SCID

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Efficient vector marking in bone marrow CD34+ cells, myeloid cells, B cells in newly diagnosed SCID
Health care spending growth slowed in 2016 following faster growth in 2014 and 2015

Deceleration in Health Care Spending Growth in 2016

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Enrollment trends drove slowdown in Medicaid and private health insurance spending growth in 2016
Paternal use of selective serotonin reuptake inhibitors before conception is associated with increased risk of attention-deficit/hyperactivity disorder in offspring

Preconception Paternal SSRI Use Linked to ADHD in Offspring

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Slightly increased ADHD risk in children born to fathers using SSRI in the three months preconception
The addition of pharmacomechanical thrombolysis does not reduce the risk of post-thrombotic syndrome among patients with acute proximal deep vein thrombosis

Pharmacomechanical Thrombolysis No Benefit in DVT

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Addition of pharmacomechanical catheter-directed thrombolysis resulted in higher risk of bleeding
For men with hemophilia B who have factor IX coagulant activity of 2 percent or less of normal value

Gene Therapy Shows Beneficial Effect in Men With Hemophilia B

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Reduction in annualized bleeding rate and in factor use with infusion of viral vector with transgene
Metabolic risk factors are associated with severe liver disease

Metabolic Risk Factors Linked to Severe Liver Disease

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Diabetes only significant predictor among alcohol risk users; alcohol use predictive for non-risk drinkers
Women who currently or recently used contemporary hormonal contraceptives have increased risk of breast cancer

Breast CA Risk Up With Recent Hormonal Contraceptive Use

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Findings from nationwide study in Denmark show small absolute increase in breast cancer risk
C-reactive protein levels are frequently elevated in patients with chronic spontaneous urticaria

CRP Levels Potentially Useful in Chronic Spontaneous Urticaria

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Elevated levels appear clinically relevant in patients with condition
The beneficial cardiopulmonary effects of walking are attenuated when walking in a traffic polluted area

Traffic Pollution Prevents Cardiac Benefits of Walking

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Findings for older men and women who are healthy, and those with COPD or ischemic heart disease
Ribociclib is beneficial for pre- and perimenopausal women with hormone receptor-positive

SABCS: Ribociclib Ups PFS in HR+ HER2− Advanced Breast Cancer

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Significant improvement in progression-free survival for pre- and perimenopausal women