Screening, Therapy Effect Varies by Breast CA Molecular Subtype
Reductions in breast cancer mortality linked to screening and treatment, but associations vary
USPSTF Questions Adolescent Idiopathic Scoliosis Screening
Finds insufficient evidence on balance of benefits and harms of screening asymptomatic 10- to 18-year-olds
HIV Screening Most Optimal at 25 Years of Age If No Risk Factors
Simulation favors screening at 25 for adolescents, young adults without identifiable HIV risk factors
Long-Term Night Shift Work Linked to Cancer Risk in Women
Dose-response pattern seen, with increased risk of breast cancer for every five years of night shift work
Type 1 IFNs May Mediate Zika Pregnancy Complications
After Zika virus infection, IFNAR signaling in conceptus inhibits development of placental labyrinth
TP53 Variants Linked to Childhood ALL, Poor Outcomes
Carrying germline variants linked to decreased event-free, overall survival; higher risk of second cancers
Maternal Folic Acid, Multivitamin Use May Cut ASD Risk in Offspring
Autism spectrum disorder risk lower in those whose moms took supplements before, while pregnant
Increased Long-Term Mortality for All Weight Categories in T2DM
Nadir at BMI of 25 to <30 kg/m²; stepwise increase to peak for patients with BMI ≥40 kg/m²
Repeated Flu Vaccinations Help Prevent Severe Infection
Annual vaccination found to lessen flu severity, hospitalizations, and death among the elderly
Kidney Injury Common After Non-Kidney Transplants in Children
High risk of AKI in first year after non-kidney solid organ transplant; in turn, increases CKD risk
