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Disrupted sleep is associated with increased amyloid-β production in adults

Disrupted Sleep Linked to Increased Amyloid-β Production

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Sleep deprivation tied to increased overnight amyloid-β-38, -40, -42 levels by 25 to 30 percent
High-sensitivity troponin assay can identify patients presenting with suspected acute coronary syndrome at very low risk for 30-day adverse cardiac events

Serial hsTnT Level IDs Risk of 30-Day Adverse Cardiac Event

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Serial levels ≤19 ng/L IDs patients presenting with suspected ACS with <1 percent risk of 30-day ACE
For patients with late-stage renal disease

Findings Could Help Reduce Risk of Calciphylaxis in Renal Disease

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Only lupus anticoagulant, combined thrombophilias are risk factors in patients with stage-5 CKD
Intrauterine exposure to methylphenidate is associated with a small increase in the risk of cardiac malformations

In Utero Methylphenidate Exposure Tied to Heart Defects

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Intrauterine exposure linked to small increase in risk of cardiac malformations based on U.S., Nordic data
Atopic dermatitis disease severity is associated with immunoglobulin G responses against Staphylococcus aureus antigens

Atopic Dermatitis Severity Tied to IgG Response to S. Aureus

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Children's responses directed against antigens with immune-modulatory functions
SERPINA1 DNA sequencing can identify alpha-1 antitrypsin deficiency

DNA Sequencing Identifies Alpha-1 Antitrypsin Deficiency

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Six rare mutations identified in seven subjects that would not have been uncovered without sequencing
Patterns of cortical β-amyloid and tau are not different for patients with Parkinson's disease who are cognitively normal or with mild cognitive impairment and for healthy adults

Cognitive Status Doesn’t Impact Cortical Aβ, Tau in Parkinson’s

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Cortical Aβ, tau does not differ in Parkinson's patients who are cognitively normal, with MCI
Omalizumab improves the efficacy of multifood oral immunotherapy among pediatric patients with multifood allergies

Omalizumab Ups Efficacy of Multifood Oral Immunotherapy

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Findings in multifood allergic pediatric patients
A deep learning algorithm can detect metastases in sections of lymph nodes from women with breast cancer; and a deep learning system has high sensitivity and specificity for identifying diabetic retinopathy

Artificial Intelligence Promising for CA, Retinopathy Diagnoses

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Two studies evaluate use; one for breast cancer, the other for diabetic retinopathy
Individuals with prior Roux-en-Y gastric bypass have blunted β-cell sensitivity to changes in glycemia

β-Cell Sensitivity to Glucose Impaired After Gastric Bypass

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Individuals with prior Roux-en-Y gastric bypass have reduced β-cell glucose sensitivity