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Hematopoietic stem/progenitor cell-derived chimeric antigen receptor T-cells are capable of long-term engraftment in a model of HIV/AIDS

HSPC-Derived CAR T-Cells Capable of Lasting Engraftment

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Chimeric antigen receptor T-cells persisted more than 2 years without measurable toxicity in primate model

December 2017 Briefing – Pathology

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Here are what the editors at HealthDay consider to be the most important developments in Pathology for December 2017. This roundup includes the latest...
Obstetrician-gynecologists should be aware of who is eligible for cascade testing

ACOG Advocates Cascade Testing for Hereditary Gene Mutations

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Ob-gyns should identify eligible patients, offer testing, and assist in decreasing barriers to testing
For children exposed to antiepileptic drugs in utero

Folic Acid Lessens Autism Risk for Fetal Anti-Epileptic Exposure

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For children exposed to antiepileptic drugs in utero, risk may be mitigated by folic acid supplementation
New classification criteria have been developed for idiopathic inflammatory myopathies

Criteria Developed for Idiopathic Inflammatory Myopathies

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Classification criteria developed from rheumatology, dermatology, neurology, pediatric clinic data
Neuroanatomic abnormalities are seen in cohorts at high risk for autism spectrum disorder

Neuroanatomic Abnormalities ID’d in Those at Risk for Autism

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Seen in carriers of deletion or duplication at 16p11.2, a common cause of autism spectrum disorder
About three-quarters of patients in California who receive End of Life Option Act drugs ingest them and die

Three-Quarters Receiving ‘End of Life Option Act’ Drugs Take Them

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Common reasons for pursuing California's EOLOA are not wanting to suffer, not being able to enjoy life
Atopic dermatitis is associated with an increased risk of developing squamous cell carcinoma

Atopic Dermatitis Associated With Higher Risk of Skin Cancer

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Individuals with a history of atopic dermatitis have a higher risk of squamous cell carcinoma development
The cumulative risk of end-stage renal disease among patients with type 1 diabetes has declined over time in Finland

Risk of ESRD in T1DM Patients Has Fallen Markedly in Finland

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Relative risk of end-stage renal disease was 0.13 in those diagnosed in 1995-2011 versus 1965-1979
Short-term exposure to ambient fine particulate matter and warm-season ozone at levels below current national air quality standards is associated with increased risk of mortality in the U.S. Medicare population

Exposure to PM2.5, Ozone at Low Levels Linked to Mortality

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Link between short-term exposure to levels below air quality standards, mortality in Medicare population