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The reduction in risk of cardiovascular death with empagliflozin is most mediated by changes in hematocrit and hemoglobin

Plasma Volume Changes May Mediate Effects of Empagliflozin

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Findings suggest reduced CV mortality risk mediated by effects on markers of plasma volume
Gastroesophageal reflux disease is associated with a higher risk of cancer in the upper aerodigestive tract among the elderly population in the United States

GERD Linked to Upper Aerodigestive Tract Cancers

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In elderly, tied to higher odds of malignancy in larynx, hypopharynx, oropharynx, nasopharynx
Colon cancer patients with elevated preoperative carcinoembryonic antigen levels that normalize after resection are not at increased risk for poor prognosis

Normalized Post-Op CEA May Help Predict Colon Cancer Prognosis

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Normalized CEA post resection not indicator of poor prognosis
For patients with high-risk indeterminate pulmonary nodes

Cancer Probability Documentation Lacking for Some at High Risk

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Documentation found to be rarely provided for high-risk indeterminate pulmonary nodes
From 2015 to 2016

CDC: 2015 to 2016 Saw Drop in Life Expectancy in United States

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Increase in rate of age-adjusted drug overdose deaths observed during same time period
In their first year

Early-Stage Cancer Diagnoses Up With ACA’s Medicaid Expansions

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Both overall and early diagnosis of cancer increased in first year of expansions
A levonorgestrel-releasing intrauterine device is effective in the majority of patients undergoing conservative treatment for low-risk endometrial cancer and complex atypical hyperplasia

Levonorgestrel IUD Feasible for Low-Risk, Early Uterine Cancer

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Majority of women responded well and returned to normal histology in six months
For healthy adults and individuals with well-controlled type 2 diabetes

DPP-4 Inhibitor Has Dissociated Effects on β-Cell Function

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Single dose of sitagliptin linked to increases in standardized insulin secretion, active GIP, GLP-1
Switching dual antiplatelet therapy from aspirin plus ticagrelor or prasugrel to aspirin plus clopidogrel after acute coronary syndrome provides benefits regardless of initial platelet reactivity

Switching Dual Antiplatelet Therapy Beneficial After ACS

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Greatest benefit seen in patients with low on-treatment platelet reactivity
Patients with various rheumatic diseases have an increased risk of dementia

Rheumatic Diseases Associated With Increased Dementia Risk

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Statistical significance in Sjögren's syndrome, lupus, OA in females; SS, psoriatic arthritis, OA in males