Hepatic Fat Accumulation May Have Causal Role in Liver Disease
Impact of genetic variants on liver damage proportional to effect on hepatic fat accumulation
Acetaminophen Use in Pregnancy Linked to Language Delay
Number of APAP tablets, urinary APAP concentration linked to increased odds of language delay in girls
Adherence to Healthy Diet May Cut Effects of Genetics on Obesity
Long-term, improved diet quality benefits weight control in those with high genetic risk of obesity
Psoriasis Is Independent Risk Factor for Comorbidity in Children
Those with psoriasis at higher risk for diabetes, liver disease, elevated lipid levels independent of obesity
Screening, Therapy Effect Varies by Breast CA Molecular Subtype
Reductions in breast cancer mortality linked to screening and treatment, but associations vary
USPSTF Questions Adolescent Idiopathic Scoliosis Screening
Finds insufficient evidence on balance of benefits and harms of screening asymptomatic 10- to 18-year-olds
HIV Screening Most Optimal at 25 Years of Age If No Risk Factors
Simulation favors screening at 25 for adolescents, young adults without identifiable HIV risk factors
Long-Term Night Shift Work Linked to Cancer Risk in Women
Dose-response pattern seen, with increased risk of breast cancer for every five years of night shift work
Type 1 IFNs May Mediate Zika Pregnancy Complications
After Zika virus infection, IFNAR signaling in conceptus inhibits development of placental labyrinth
TP53 Variants Linked to Childhood ALL, Poor Outcomes
Carrying germline variants linked to decreased event-free, overall survival; higher risk of second cancers