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The concept of internet gaming disorder and the pathways leading to it are unclear

Questions Surround Concept of Internet Gaming Disorder

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Several interacting internal factors and external factors are required for developing IGD
Elevated fibroblast growth factor 23 is associated with increased risk of recurrent major cardiovascular events in patients after an acute coronary syndrome

High FGF-23 Linked to Recurrent Cardiac Events After ACS

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FGF-23 in top quartile independently linked to greater risk of CV death, heart failure hospitalization
For patients with severe β-thalassemia

Gene Therapy Found to Be Promising for β-Thalassemia

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CD34+ cells transduced with BB305 vector lowered or eliminated need for red-cell transfusions
Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle

Young Adults With T1DM Show Muscle Metabolic Deficiencies

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Lower mitochondrial oxidative capacity in skeletal muscle of physically active young adults with T1DM
A cell-based biomedical tattoo can detect hypercalcemia associated with cancer in a murine model

Cellular Biomedical Tattoo Can ID Hypercalcemia-Linked Cancer

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Hypercalcemia linked to cancer can be detected in murine model using cell-based diagnostic system
Mild traumatic brain injury is associated with increased risk of Parkinson's disease among military veterans

Mild TBI May Increase Risk of Parkinson’s Disease

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In adjusted analyses, increased risk seen for all-severity TBI, mild TBI, moderate-severe TBI
Males with BRCA mutations have increased incidence of malignant disease

Males With BRCA Mutations Have Increased Risk of Certain Cancers

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Increased incidence of malignant disease, specifically prostate, melanoma, pancreas, breast cancers
Transcription factors seem to operate across gene loci

TFs Operate Across Gene Loci Within Disease Phenotypes

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Epstein-Barr virus EBNA2 protein binds to multiple loci of genome, increasing risk of 7 serious diseases
In a position paper published online April 17 in the Annals of Internal Medicine

Recommendations Developed on Gender Equity in Medicine

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ACP supports equitable physician compensation based on comparable work at each stage of career
The estimated annual cost of drug-related morbidity and mortality resulting from nonoptimized medication therapy is more than half a trillion dollars in the United States

Nonoptimized Drug Therapy Costs More Than $500 Billion Annually

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After initial Rx use, average cost of individual having treatment failure, new medical problem over $2,000