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Women whose infants have congenital heart defects have an increased risk of cardiovascular hospitalization later in life

Infant Heart Defects May Be Early Marker of Future CVD in Mothers

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Mothers of infants with congenital heart defects are more likely to have cardiovascular hospitalization
A primary mechanism for APOE gene-mediated plaque formation may result from apoE aggregation

apoE Aggregation May Impact apoE-Mediated Plaque Formation

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Anti-human apoE-4 antibody preferentially binds unlipidated aggregated apoE over lipidated version
A Zika vaccine could substantially prevent future outbreaks through a combination of direct protection and indirect transmission reduction

Zika Vaccine Could Essentially Eliminate Prenatal Infection

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Model shows vaccine is effective through a combo of direct protection, indirect transmission reduction
The risk for myocardial infarction or stroke remains higher after laboratory-confirmed S. pneumoniae or influenza

Rate of MI, Stroke Higher After Respiratory Infection

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Substantially increased risk of myocardial infarction, stroke in week after S. pneumoniae or influenza
The office-based

Montreal Parkinson Risk of Dementia Scale Deemed Accurate

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All eight items of office-based scale independently predict development of dementia in Parkinson's
In the Midwest and Appalachia there are areas where progress against lung cancer mortality among women is lagging compared with the rest of the nation

Lag in Progress Against Lung CA Mortality in Midwest, Appalachia

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Findings based on rates among women versus steady decline seen nationally
Metabolomic profiling highlights potential mechanisms to explain coffee's health effects

Novel Metabolites Provide Insight to Health Benefits of Coffee

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Findings may provide insight into mechanisms behind coffee's health effects
There are significant improvements in health-related quality of life following islet transplantation in patients with type 1 diabetes complicated by severe hypoglycemia

Islet Transplantation Improves Quality of Life in T1DM

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Also decreases severe hypoglycemic events; findings among T1DM patients participating in a phase 3 trial
For patients with major depressive disorder

Relapse in Major Depression Linked to Brain Cortical Changes

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Significant decline of insular volume and dorsolateral prefrontal from baseline to follow-up
A previously unrecognized interstitium has been identified in human tissues

Novel Interstitium Has Been Identified in Human Tissues

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Structure demonstrated to be part of the submucosa, supported by network of thick collagen bundles