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For patients with discogenic low back pain

Intradiscal Electrothermal Therapy Cost-Effective

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Findings based on comparison to femoral ring allograft for discogenic low back pain
Local steroid injection is effective for treatment of carpal tunnel syndrome and improves hand function

Steroid Injection Betters Hand Function With Carpal Tunnel

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Nocturnal wrist splinting also effective, but doesn't improve hand function
For patients with noncancer pain and opioid-induced constipation

Naloxegol Has No Effect on Opioid Dose in Opioid-Tied Constipation

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Centrally-mediated analgesia was maintained during treatment with naloxegol in noncancer pain, OIC
Insurers have the bargaining power to reduce provider prices in highly concentrated provider markets

Insurer Market Power Lowers Providers’ Prices

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Evidence seen for specialists in markets with high provider, insurer concentration
The American College of Physicians does not support the legalization of physician-assisted suicide

ACP Does Not Support Legalization of Assisted Suicide

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Legalization would affect trust in the patient-physician relationship, and in the medical profession
From 2000 to 2015

Total of 0.21 Years Lost Due to Opioid-Related Poisoning Deaths

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Drug-related poisoning deaths up from 2000 to 2015, with most of the increase due to opioid deaths
Opioid dependence/abuse is a critical public health issue among children in the United States

AAP: Opioid Dependence/Abuse Public Health Issue for Children

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ER visits for opioid dependence/abuse increased from 32,235 in 2008 to 49,626 in 2013
Spin in biomedical literature (also referred to as "science hype") is prevalent

‘Science Spin’ Found Prevalent in Biomedical Literature

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Nature of spin varies, with highest variability in prevalence of spin seen in trials
Physicians spend almost six hours per day in the electronic health record

Doctors Spend Almost Six Hours Per Day on EHR Tasks

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Clerical and administrative tasks including order entry, billing account for almost half of hours
Most physicians on Twitter with a financial conflict of interest and frequent tweets mention specific drugs for which they have a conflict

Physicians Tweeting About Drugs May Have Conflict of Interest

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Physicians with financial conflict of interest often mention specific drugs for which they have a conflict