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Preprint, Peer-Reviewed Pairs of Studies Generally Concordant

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Sample sizes, primary end points, interpretations mainly concordant for studies published on medRxiv, then in journals

RSNA: Corticosteroid Injections Appear to Worsen Knee Osteoarthritis

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Corticosteroids linked to progression of knee OA based on whole-organ magnetic resonance imaging scores, KL grade

Antidepressants Have Small Benefit for Pain, Function in OA

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However, total adverse events occur more often in patients receiving antidepressants versus placebo

ACR: Genicular Nerve Block Offers Short-Term Pain Relief for Knee OA

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Improvements seen in pain scores for patients receiving genicular nerve block at two, four, eight, and 12 weeks

FDA: Patients Should Be Cautious When Using Online Pharmacies to Buy Meds

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Red flags include pharmacies that do not require a doctor's prescription or have a licensed pharmacist to answer questions

FDA Oversight of Clinical Trials Described as ‘Grossly Inadequate’

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Article describes inadequate oversight relating to development of COVID-19 vaccines and predating the pandemic

Multidimensional Factors Shaped Physician Stress During Pandemic

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Physicians' perceptions of occupational stress at individual level were shaped by stressors within and across four levels

Outcomes Similar for Total Ankle Replacement, Ankle Fusion in OA

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No clinically or statistically significant difference seen in mean change in Manchester-Oxford Foot Questionnaire walking/standing domain scores

Delivery Methods Compared for Osteoarthritis Intervention

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Pain reduction seen for in-person or digital delivery of education and exercise instruction for hip, knee osteoarthritis

Hip Brace May Slow Hip Displacement in Children With Cerebral Palsy

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Improvements also seen in caregiver-reported quality of life for children with nonambulatory cerebral palsy