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December 2015 Briefing – OBGYN & Women’s Health

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Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for December 2015. This roundup...
Third-trimester screening for alloimmunization in Rhesus c-negative women improves detection and treatment of hemolytic disease of the fetus and newborn

Third-Trimester Screen Detects Late Alloimmunization

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Detection through additional screening facilitates timely treatment
Metformin reduces soluble fms-like tyrosine kinase 1 and soluble endoglin secretion from primary human tissues

Metformin Looks Promising in the Treatment of Preeclampsia

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Reduces sFlt-1 and sENG secretion from primary human tissues; reduces endothelial dysfunction
Some authors of a published study that claimed nitroglycerin might boost bone density in older women have asked that the study be retracted

Researchers Call for Retraction of Nitroglycerin-Bone Density Study

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Investigation found that lead author fabricated data used to support the finding
Planned out-of-hospital birth is associated with higher perinatal mortality and with increased odds of some adverse neonatal outcomes compared with planned in-hospital birth

Perinatal Mortality Higher for Planned Out-of-Hospital Birth

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But absolute risk of perinatal death is low for both in-hospital and out-of-hospital planned births
Physician burnout is the top issue for physicians in 2015

AMA: Burnout Is Top Issue for Physicians in 2015

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More than half of docs report at least one symptom of burnout; efforts being undertaken to address burnout
Primary debulking surgery and chemotherapy in an optimal timeframe is associated with the longest survival time for elderly women with advanced ovarian cancer

Surgery, Chemo Best for Elderly With Advanced Ovarian Cancer

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Longest survival time for primary debulking surgery, chemotherapy with optimal timeframe
Hodgkin's lymphoma survivors have an increased risk of a second cancer

Second Cancer Risk Persists for Hodgkin’s Lymphoma Survivors

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Increased risk compared with the general population even for those receiving more recent treatments
Ultrasound and mammography appear equally likely to detect breast cancer

Breast CA Detection Comparable for Ultrasound, Mammography

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But ultrasound has more false positives, researchers find
BRCA1/2 mutation carriers have increased risk of contralateral breast cancer (CBC)

Early First Cancer in BRCA1/2 Ups Risk in Opposite Breast

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For mutation carriers, age at diagnosis of first cancer predicts contralateral breast cancer risk