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Elevation in white blood cell BRCA1 promoter methylation is associated with high-grade serous ovarian cancer

BRCA1 Promoter Methylation Tied to High-Grade Serous Ovarian CA

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Elevated normal tissue BRCA1 promoter methylation associated with high-grade serous ovarian CA risk
Transdermal estradiol plus intermittent micronized progesterone can prevent clinically significant depressive symptoms among euthymic perimenopausal and early postmenopausal women

Transdermal Estradiol May Help Prevent Depressive Symptoms

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Effects of TE, micronized progesterone seen in perimenopausal, early postmenopausal women
Children with psoriasis have an increased risk of comorbidities compared to children without psoriasis

Psoriasis Is Independent Risk Factor for Comorbidity in Children

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Those with psoriasis at higher risk for diabetes, liver disease, elevated lipid levels independent of obesity
Acetaminophen use in pregnancy is associated with language delay among girls

Acetaminophen Use in Pregnancy Linked to Language Delay

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Number of APAP tablets, urinary APAP concentration linked to increased odds of language delay in girls
Improving adherence to healthy dietary patterns may help reduce the genetic association with weight gain

Adherence to Healthy Diet May Cut Effects of Genetics on Obesity

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Long-term, improved diet quality benefits weight control in those with high genetic risk of obesity
For young adults without known risk factors

HIV Screening Most Optimal at 25 Years of Age If No Risk Factors

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Simulation favors screening at 25 for adolescents, young adults without identifiable HIV risk factors
There is a positive association between long-term night shift work and the risk of several common cancers for women

Long-Term Night Shift Work Linked to Cancer Risk in Women

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Dose-response pattern seen, with increased risk of breast cancer for every five years of night shift work
There is urban and rural variation in fertility-related behavior among U.S. women

Urban, Rural Variation in Fertility-Related Behaviors for U.S. Women

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Younger average age at first intercourse in rural areas; more women in rural areas had ≥1 birth
The contributions of screening and treatment to decreases in breast cancer mortality vary by molecular subtype

Screening, Therapy Effect Varies by Breast CA Molecular Subtype

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Reductions in breast cancer mortality linked to screening and treatment, but associations vary
Type 1 interferons may mediate pregnancy complications in the context of congenital Zika virus infection

Type 1 IFNs May Mediate Zika Pregnancy Complications

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After Zika virus infection, IFNAR signaling in conceptus inhibits development of placental labyrinth