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At least 16.8 million Americans could potentially benefit from the type of aggressive blood pressure treatment pursued under the Systolic Blood Pressure Intervention Trial (SPRINT). The findings were published online Nov. 9 in the New England Journal of Medicine to coincide with presentation at the annual meeting of the American Heart Association

AHA: Reducing Blood Pressure Target Could Increase Benefits

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Risk of CVD was lowered by 25 percent, while all-cause mortality risk was reduced 27 percent
Combination therapy of endovascular revascularization and supervised exercise is associated with greater improvements than supervised exercise alone for patients with intermittent claudication. The findings were published in the Nov. 10 issue of the Journal of the American Medical Association

AHA: Combo Tx Ups Benefits in Intermittent Claudication

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Greater improvements in waking distances, quality of life with revascularization plus exercise
Short sessions of high-intensity exercise may provide more health benefits for people with type 2 diabetes than longer bouts of less intense activity

AHA: Short, Intense Bouts of Exercise More Beneficial in T2DM

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Research suggests brief but harder workouts may provide better blood glucose control
Patients with mechanical heart valves may benefit from managing their own oral anticoagulant therapy

Self-Managing Anticoagulation May Benefit Heart Valve Patients

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Study found self-monitoring was linked to a lower risk of death after five years
Three renal biomarkers

Three Renal Biomarkers Predict Outcome in Diabetes

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AKI, albuminuria, eGFR considered separately or together can predict adverse outcomes in diabetes
Lack of sleep may be a gateway to chronic kidney disease

ASN: Insufficient Sleep Might Increase Risk of Kidney Disease

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Five hours or less a night linked to reduced organ function in women
Proton pump inhibitors appear to be linked with increased risk of chronic kidney disease

ASN: PPIs Linked to Higher Risk of Chronic Kidney Disease

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But studies weren't designed to prove proton pump inhibitors are responsible for the increase
Exercise capacity and heart rate responses to exercise are effective predictors of short-term outcome among patients with stable coronary artery disease

Exercise Capacity, Heart Rate Response Predict CAD Outcomes

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Addition of exercise risk score to established risk model enhances discrimination
For patients with chronic kidney disease (CKD)

ASN: Telenephrology Improves Visit Compliance in CKD

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Greater frequency of attending appointments; no difference in the incidence of composite outcomes
Patients who shared a financial incentive with their doctor to lower their levels of low-density lipoprotein cholesterol achieved a statistically significant reduction after a year of treatment. These findings were published in the Nov. 10 issue of the Journal of the American Medical Association

AHA: ‘Cash for Lower Cholesterol’ Program May Work

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Cooperation is key to program's success, but benefits are modest