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For preteen children

Social Impact for Untreated Infantile Hemangiomas

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Preteens with untreated IHs have higher social anxiety scores, lower social initiative scores
For patients with immunoglobulin A nephropathy

Addition of Immunosuppression No Benefit in IgA Nephropathy

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No improvement in outcomes, more adverse effects for intensive supportive care + immunosuppression
The addition of lixisenatide to usual care does not impact the rate of major cardiovascular events or other serious adverse events among patients with type 2 diabetes and a recent acute coronary syndrome

Lixisenatide Doesn’t Affect Cardiovascular Risk in T2DM

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Findings among patients with type 2 diabetes and recent acute coronary syndrome
Less frequent laboratory monitoring may be safe for patients receiving isotretinoin for acne as changes in mean values of several laboratory tests do not meet a priori criteria for high-risk

Evidence Doesn’t Support Monthly Labs With Isotretinoin

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Significant changes in values of several laboratory tests, but changes don't meet high-risk criteria
For critically ill patients

Transfusion, Mortality Link Varies With Hemoglobin Levels

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For ICU patients, hemoglobin level thresholds vary with presence of comorbid heart disease
In the United States

Burden, Costs of Gastrointestinal, Liver Disease Estimated in U.S.

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GI hemorrhage is most common diagnosis leading to hospitalization, with cost of $5 billion in 2012
The U.S. Preventive Services Task Force has found that there is currently insufficient evidence to weigh the benefits and harms of visual skin cancer screening in adults. These findings form the basis of a draft recommendation statement published online Nov. 30 by the USPSTF.

USPSTF: Insufficient Evidence for Visual Skin Cancer Screening

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Task Force finds insufficient evidence to weigh benefits and harms of visual screening in adults
Children born by planned cesarean delivery appear to have slightly higher odds of developing asthma than those born through vaginal delivery

Asthma Risk Up Slightly for Planned C-Section Children

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But second study finds countries with low C-section rates had higher mortality rates for infants, mothers
Continuous positive airway pressure and mandibular advancement devices each produce a modest reduction in both systolic and diastolic blood pressure rates in patients with obstructive sleep apnea

CPAP, Mandibular Advancement Devices Both Help Lower BP

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Researchers find both common treatments produce modest BP decreases in sleep apnea patients
Adding metformin to insulin therapy won't boost glycemic control for overweight teens with type 1 diabetes

Metformin Does Not Boost Glycemic Control in T1DM

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Small, but temporary, beneficial effect from metformin was seen early on