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Comorbidity burden is strongly and independently associated with pathological upgrading/up staging in men with clinically low-risk prostate cancer

Comorbidity Tied to Prostate Cancer Upgrading, Up Staging

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Findings among men with clinically low-risk prostate cancer
For patients with type 1 diabetes

Digital Assistant in Closed-Loop Control Mode Beneficial in T1DM

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Overnight-only and 24/7 closed-loop control reduce hypoglycemia, increase time in range
For patients with hypertriglyceridemia

LDL Reduction in Hypertriglyceridemia Varies Per Statin

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Greater LDL-C reductions for rosuvastatin 10-40 mg vs equal, double doses of atorvastatin, simvastatin
For adult women with breast cancer

In Breast CA, Cardiotoxicity Up With Trastuzumab-Based Chemo

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Increased risk of cardiotoxicity for trastuzumab with nonanthracycline chemo, sequential tx
A recently approved

AACR: Cologuard Can Detect CRC in Previously Unscreened Patients

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Cologuard may help spot tumors, but colonoscopy still preferred option
Teenagers with depression who refuse antidepressants may benefit from cognitive behavioral therapy

CBT Helps Teens With Depression Who Refuse Antidepressants

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Cognitive behavioral therapy can help improve mood without drugs
The BRCA1 gene mutation may also be tied to potential fertility issues

BRCA1 Mutation May Reduce Women’s Fertility

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The BRCA1 mutation may speed the aging of a woman's ovaries
There may be a link between certain oral bacteria and a heightened risk of pancreatic cancer

AACR: Study Ties Oral Bacteria to Pancreatic Cancer Risk

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Two strains of oral bacteria -- P. gingivalis and A. actinomycetemcomitans -- linked to higher risk
A cluster of rare bloodstream infections was discovered by Illinois health officials while investigating an outbreak in Wisconsin.

Ten Cases of Rare Bloodstream Infection Reported in Illinois

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Cases of infection from the bacterium Elizabethkingia included six deaths
Metformin is associated with reduced cardiovascular mortality compared with sulfonylureas

Lower CVD Mortality for Metformin Versus Sulfonylureas

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Large analysis found up to 40 percent lower risk of heart disease mortality versus sulfonylureas