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February 2016 Briefing – Neurology

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Here are what the editors at HealthDay consider to be the most important developments in Neurology for February 2016. This roundup includes the latest...
Zika virus infection may be associated with incidence of Guillain-Barré syndrome

Zika Infection Linked to Guillain-Barré Syndrome

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Most patients diagnosed with Guillain-Barré during Zika outbreak have Zika virus IgM
For adults aged 80 years or older

Dementia Incidence Higher Than CHD in Very Elderly

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Among adults aged ≥80 years, about 64 percent of those who died had prior diagnosis of dementia
Individuals with a history of syncope may be almost twice as likely as others to get into a car crash

Car Crash Risk May Nearly Double in Patients With Syncope

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But whether lost consciousness is the cause isn't clear, researchers say
In an article published online Feb. 23 in the Annals of Internal Medicine

Suggestions for Optimizing Practice Feedback Effectiveness

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Practice feedback interventions relate to nature of desired action, feedback display, delivery of feedback
Intellectual enrichment (high education and high midlife cognitive activity) has effects on biomarkers of Alzheimer's disease in older adults

Active Mind May Delay Alzheimer Symptoms, but Not Disease

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High midlife cognitive activity tied to lower amyloid deposition in APOE4 carriers with high education
A small reduction as the primary composite outcome may not justify the increased adverse events and costs associated with an intervention targeting systolic blood pressure less than 120 mm Hg

Authors Urge Caution Before Adopting New Systolic BP Goals

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Small absolute benefit seen in SPRINT must be balanced with increased adverse event rates
Many Ebola survivors have neurological symptoms that last long after other signs of the infection are gone

AAN: Ebola May Leave Lasting Neurological Symptoms

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Six months after active illness, headaches, memory loss, depression were still being reported
Gastrointestinal bowel obstruction is associated with worse prognosis for patients with acute ischemic stroke

ASA: Certain Factors Up Odds of Post-Stroke Bowel Obstruction

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Post-acute ischemic stroke GI bowel obstruction predicts in-hospital complications, disability, death
Antibiotic-associated encephalopathy can be classified into three unique clinical phenotypes

Three Classes of Antibiotic-Associated Encephalopathy ID’d

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Three unique clinical phenotypes correlate with underlying pathophysiologic mechanisms