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For patients with Parkinson's disease receiving levodopa therapy and experiencing end-of-dose motor fluctuations

Opicapone As Levodopa Adjunct Cuts Motor Fluctuations in PD

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In Parkinson's disease, 50-mg/day opicapone linked to significant reduction in mean daily off-time
From 1996 to 2013 there were considerable increases in personal health care spending in the United States

Personal Health Care Spending Continues to Soar in the U.S.

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Highest spending on diabetes, ischemic heart disease, and low back and neck pain in 2013
For critically ill patients with convulsive status epilepticus

Induced Hypothermia Futile in Convulsive Status Epilepticus

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At 90 days, functional outcome of critically ill patients on mechanical ventilation not significantly better
Studies reporting pharmacological and adjuvant analgesic modalities for post-craniotomy pain control have significant divergence in their research methods

Research for Post-Craniotomy Analgesia Uneven in Quality

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Finding of superior pain relief with opioids, with no significant side effects, but study quality deemed low
Ocrelizumab

Ocrelizumab Targets Role of B Cells in Multiple Sclerosis

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Studies show lower relapse rate in relapsing MS, lower rate of progression in primary progressive dz
A U.S. Department of Veterans Affairs Extension for Community Healthcare Outcomes program is feasible for increasing comfort in managing common sleep complaints

VA ECHO Program Feasible for Management of Sleep Disorders

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Most respondents anticipated sleep practice change from participation in virtual learning community
Health care provider burnout is negatively associated with quality and safety of health care

Health Care Provider Burnout Negatively Affects Quality, Safety

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Health care provider burnout negatively linked to quality and safety of health care
For adults

Therapeutic Hypothermia Benefits Adults With TBI

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Higher mortality, trend for deterioration in neurologic outcome for children undergoing hypothermia
Participation in physical activity within seven days after injury is associated with reduced rates of persistent postconcussive symptoms

Risk of Postconcussive Symptoms Down With Early Exercise

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Participation in physical activity within seven days after injury linked to reduced rates of PPCS
For patients with coronary heart disease

Noncardiovascular Cause of Death More Common in CHD Patients

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Predictors of noncardiac death include older age, inducible ischemia, higher heart rate, statin nonuse