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Conventional clinical trials are unable to detect clinically important heterogeneity in intensive blood pressure treatment effects

Conventional Trials Can’t Detect Heterogeneity in BP Tx Effects

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Clinically important heterogeneity in intensive BP tx effect can be ID'd in sequential randomization trials
The Zika virus is not likely to gain a foothold in the United States as it did in Brazil and other Latin American countries

Major Zika Outbreak Considered Unlikely in the United States

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Higher standard of living reduces odds the virus-carrying mosquitoes will thrive

December 2016 Briefing – Neurology

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Here are what the editors at HealthDay consider to be the most important developments in Neurology for December 2016. This roundup includes the latest...
For patients undergoing autologous breast reconstruction

No Effect for BUP TAP Catheter on Chronic Pain After Breast Recon

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No difference in chronic postsurgical pain incidence for TAP catheter delivering bupivacaine, saline
Among U.S. adults

Iron Deficiency Anemia Ups Risk of Hearing Loss in U.S. Adults

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After adjustment for sex, adults with IDA have increased odds of SNHL, combined hearing loss
The oral selective inhibitor of MAPK kinase 1 and 2

Selumetinib Active in Children With Neurofibromatosis Type 1

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Patients were able to receive selumetinib on long-term basis; maximum tolerated dose 25 mg/m²
Treatment with autologous chimeric antigen receptor-engineered T cells targeting the tumor-associated antigen interleukin-13 receptor alpha 2 is associated with tumor regression in recurrent multifocal glioblastoma

Case Report: Adoptive T-Cell Tx Shows Promise in Glioblastoma

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Tumors regressed after intracranial infusions of T cells engineered to target tumor-associated antigen
Bell's palsy is the only prespecified adverse event associated with the MenACWY-CRM quadrivalent meningococcal conjugate vaccine

Bell’s Palsy Tied to Quadrivalent Meningococcal Vaccine

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Increased risk for Bell's palsy in those with concomitant administration of other vaccines
Moderate post-lunch napping is tied to better cognition in older adults

Post-Lunch Napping Tied to Better Cognition in Elderly

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Moderate nappers scored higher than non-nappers, short nappers, extended nappers
For women surviving into late life

Is Dementia in Older Women Tied to 20-Year Rate of Weight Loss?

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Rate of loss over 20 years linked to development of MCI/dementia in women surviving past 80