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Within a cohort of patients insured through TRICARE

Opioid Rx Frequently Issued for Nonspecific, Spinal Conditions

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Spine, orthopedic disorders most prominent among categories of conditions linked to initial opioid Rx
Lifetime costs of care are substantially increased for individuals with dementia

Families Shoulder Majority of Costs Related to Dementia Care

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Reducing functional decline or behavioral and psychological symptoms leads to lower lifetime costs
Enhancing physical activity level and function can decrease the fear of falling among elderly patients

Increasing Physical Activity, Function Can Decrease Fall Fears

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Activities of daily living and mobility among predictors of fear of falling in geriatric patients
During the past two decades

Increase in Survival Without Severe Disability for Preemies

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However, children born preterm still have high risk for developmental delay
De novo KCNB1 missense and loss-of-function variants are associated with neurodevelopmental disorders

Phenotype Varies for Presumed Pathogenic Variants in KCNB1

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De novo mutations in KCNB1 associated with variable neurodevelopmental disorder
Adoption of specialty access standards has not improved access to specialists

Specialist Access No Better With Adoption of Access Standards

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No notable improvement in timely access to specialty services following implementation of standards
Many studies used to support U.S. Food and Drug Administration approval of high-risk medical device modifications are not controlled; and efficacy of drugs granted accelerated approval is often confirmed three years after approval

Studies Used for FDA Approval of Device Changes Often Low Quality

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And, efficacy of drugs granted accelerated approval often confirmed only years after approval
Zika virus infection is associated with increased incidence of neurological syndromes

Diverse Spectrum of Neurologic Syndromes Seen With Zika

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Increase in admissions for Guillain-Barré syndrome, encephalitis compared with before outbreak
Intraindividual variability of reaction time is independently associated with mortality

Intraindividual Variability in Reaction Time Tied to Mortality

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Independent link identified, which changed very little after excluding incident dementia cases
There is a strong relationship between high on-clopidogrel platelet reactivity and two-year ischemic and bleeding outcomes after drug-eluting stent implantation

High Platelet Reactivity Tied to Ischemic, Bleeding Outcomes

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Findings based on two-year follow-up after drug-eluting stent implantation