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Severe functional limitations are reported among children with microcephaly and laboratory evidence of Zika virus infection in infancy

Functional Limitations Ongoing With Congenital Zika

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All 19 children reported one of six adverse outcomes; 12 had three to five outcomes at 19 to 24 months
A bivalent meningococcal B vaccine targeting factor H-binding protein elicits bactericidal responses against diverse meningococcal B strains after two and three doses in adolescents and young adults

Bivalent Meningococcal B Vaccine Safe, Immunogenic

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Elicits bactericidal responses against diverse meningococcal B strains in teens, young adults
Disrupted sleep is associated with increased amyloid-β production in adults

Disrupted Sleep Linked to Increased Amyloid-β Production

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Sleep deprivation tied to increased overnight amyloid-β-38, -40, -42 levels by 25 to 30 percent
Intrauterine exposure to methylphenidate is associated with a small increase in the risk of cardiac malformations

In Utero Methylphenidate Exposure Tied to Heart Defects

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Intrauterine exposure linked to small increase in risk of cardiac malformations based on U.S., Nordic data
For patients undergoing surgery

Gabapentin Doesn’t Cut Time to Pain Cessation After Surgery

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But perioperative gabapentin is linked to increase in rate of opioid cessation after surgery
Patterns of cortical β-amyloid and tau are not different for patients with Parkinson's disease who are cognitively normal or with mild cognitive impairment and for healthy adults

Cognitive Status Doesn’t Impact Cortical Aβ, Tau in Parkinson’s

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Cortical Aβ, tau does not differ in Parkinson's patients who are cognitively normal, with MCI
For patients with Parkinson's disease

High-Intensity Treadmill Exercise Feasible in Parkinson’s Disease

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Mean change in Unified Parkinson's Disease Rating Scale motor score lower for high-intensity exercise
Health care spending growth slowed in 2016 following faster growth in 2014 and 2015

Deceleration in Health Care Spending Growth in 2016

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Enrollment trends drove slowdown in Medicaid and private health insurance spending growth in 2016
Paternal use of selective serotonin reuptake inhibitors before conception is associated with increased risk of attention-deficit/hyperactivity disorder in offspring

Preconception Paternal SSRI Use Linked to ADHD in Offspring

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Slightly increased ADHD risk in children born to fathers using SSRI in the three months preconception
Parkinson's disease patients with depression have impaired white matter integrity

Impaired White Matter Integrity for Depression in Parkinson’s

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Reduced fractional anisotropy values in left anterior corona radiata, left cingulum of depressed patients