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Early Adoption of DOAC Dashboard Reduces Off-Label Prescribing

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Adoption of DOAC population management tool dashboard before July 2018 linked to decline in off-label dosing prescriptions

Guidelines Provided for Diagnosis of Pediatric, Late-Onset Multiple Sclerosis

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Unique biological features seen in children younger than 18 years, adults older than 50 years compared with typical adult-onset MS

Maternal Influenza Infection in Pregnancy Tied to Seizures in Offspring

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Significantly increased risk for seizures and febrile convulsions, but not epilepsy, observed in offspring

Extreme Temperature-Related Deaths Set to Increase by Mid-21st Century

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Greater increases projected from the current period to mid-21st century for non-Hispanic Black versus White adults

Review Compares Drug Interventions for Acute Migraine Treatment

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Eletriptan most effective for pain freedom at two hours in head-to-head comparisons, followed by rizatriptan, sumatriptan, and zolmitriptan

One in Three Retired Football Players Report Perceived Chronic Traumatic Encephalopathy

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Perceived chronic traumatic encephalopathy doubles risk for suicidality

Higher Burden of Comorbidity Linked to Worse Clinical Outcomes in MS

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Presence of three or more comorbidities, two or more cardiometabolic comorbidities, one psychiatric disorder linked to evidence of disease activity

Childhood ADHD Tied to Lower Cognitive Performance in Adulthood

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Findings seen at age 40 years compared with healthy controls, with fewer cognitive deficits seen for those with subthreshold childhood ADHD

Paternal Antiseizure Rx Use at Conception Does Not Pose Risk to Offspring

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No clear evidence seen for adverse impact of paternal antiseizure medication use on offspring outcomes

High Levels of Well-Being Protect Against Cardiovascular Disease

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General happiness plus satisfaction with family, friendships, health, and finances tied to CVD risks