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Two patients diagnosed with acute flaccid myelitis and upper-extremity neuropathy who were treated with peripheral nerve transfer continue to demonstrate functional recovery at two years

Nerve Transfer Promising for Acute Flaccid Myelitis Patients

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Two children with AFM who underwent surgery for nerve transfer show functional recovery at two years
The first generic version of Sabril (vigabatrin) has been approved by the U.S. Food and Drug Administration to prevent complex partial seizures in adults and children aged 10 years and older with epilepsy.

FDA Approves First Generic Version of Epilepsy Drug Sabril

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Generic equivalents held to same vigorous manufacturing standards as brand-name drugs
Due to the federal government shutdown

FDA Down to 5 Weeks of Funding to Review New Drug Applications

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Agency cannot accept new fees or applications until the shutdown is over
For relapsing-remitting multiple sclerosis

Risk for Conversion of MS Varies With Different Therapies

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Lower risk for conversion for initial treatment with fingolimod, alemtuzumab, or natalizumab
Adoption of advanced health information technology capabilities is inconsistent across health care systems

Adoption of Advanced Health IT Capabilities Inconsistent

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Degree of EHR standardization strongest predictor of health information technology adoption
In older adults

High Levels of Activity, Motor Ability Linked to Better Cognition

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Findings seen in older adults; independent correlations remained for those with Alzheimer disease
For patients with relapsing-remitting multiple sclerosis

Stem Cell Transplant Slows Progression of Multiple Sclerosis

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Findings from small randomized trial comparing nonmyeloablative HSCT with disease-modifying tx
Breakdown of the blood-brain barrier may be an early biomarker of cognitive dysfunction

Breakdown of Blood-Brain Barrier May Drive Dementia

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Leaky brain capillaries tied to cognitive dysfunction, independent of protein markers for dementia
Ethical principles are discussed in an updated Ethics Manual

American College of Physicians Releases 7th Edition of Ethics Manual

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Manual focuses on patient-physician relationship in different scenarios, including telemedicine
Patients with Tourette syndrome or chronic tic disorder have an increased risk for developing at least one metabolic or cardiovascular disorder

Cardiometabolic Risk Up With Tourette, Chronic Tic Disorder

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Higher risks seen for obesity, type 2 diabetes, circulatory system diseases