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The absence of haptoglobin may be a marker of poor neonatal outcomes among preterm newborns exposed to in utero inflammation

Haptoglobin Expression Tied to Outcomes in Preterm Newborns

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Worse outcomes in preemies lacking haptoglobin who were exposed to inflammation in utero
Use of the orally administered β-site amyloid precursor protein-cleaving enzyme 1 inhibitors

Verubecestat, Atabecestat Not Beneficial for Preventing Alzheimer Disease

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Two trials show lack of effectiveness versus placebo for preclinical Alzheimer disease
Consumer devices that claim to help assess

FDA Warns of Consumer Devices That Claim to Diagnose Concussion

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Tools include smartphone apps marketed to coaches or parents for use during sporting events
The latest edition of the American College of Radiology Appropriateness Criteria has been released and includes 188 diagnostic imaging and interventional radiology topics

New, Revised Topics Released in ACR Appropriateness Criteria

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New topics relate to clinically suspected vascular malformation of extremities, gestational trophoblastic disease
Proximity to major roadways and prenatal/early life exposure to particulate matter <2.5 µm and ozone are associated with childhood developmental delays

Proximity to Major Roadways Impacts Child Development

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Increased risk for child developmental delays also seen with prenatal exposure to PM2.5, ozone
Cortical lesion development surpasses white matter lesion accrual in multiple sclerosis

Cortical Lesions in Multiple Sclerosis Tracked With 7.0-T MRI

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Development of cortical lesions surpassed that of white matter lesions, linked to neurologic disability
In patients with myalgic encephalomyelitis/chronic fatigue syndrome

No Benefit Seen With Rituximab for Chronic Fatigue Syndrome

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B-cell depletion using several rituximab infusions over 12 months not linked to clinical improvement
There is no clinically meaningful long-term association between pregnancy history and age-related change in cognitive function

Pregnancy History Not Likely Tied to Later Cognitive Function

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Authors say childbearing decisions and timing have no long-term impact on cognitive function
The U.S. Food and Drug Administration warned on Tuesday that there have been reports of teens experiencing seizures following the use of electronic cigarettes.

FDA Reports Cases of Seizures Among Young Vapers

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Agency review revealed 35 reported cases of seizures following use of e-cigarettes since 2010
For patients with relapsing-onset multiple sclerosis

Beta Interferon Tied to Lower Mortality in Relapsing-Onset MS

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Increased survival seen with more than three years of beta interferon exposure but not lower exposure