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Guidance has been updated for the health supervision of children with neurofibromatosis type 1

AAP Updates Guidance for Care in Neurofibromatosis Type 1

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Report describes criteria for diagnosis, role of genetic testing, possible health manifestations
Limited evidence suggests that nusinersen treatment provides long-term benefits for children with later-onset spinal muscular atrophy

Nusinersen Promising for Later-Onset Spinal Muscular Atrophy

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Phase 1/2 studies reveal long-term improvement in motor function for children with SMA type II and III
Obesity is associated with differences in gray matter volumes in the brain

Obesity May Impact the Form and Structure of the Brain

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Gender appears to be a modifier of the link between fat percentage and the size of specific brain structures
For patients with amyotrophic lateral sclerosis

African-Americans With ALS Survive Longer Than Caucasians

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Difference no longer significant when outcome is death or tracheostomy and invasive ventilation
Despite a potential increased risk for stroke in patients with diabetes

Acetaminophen Safe as First-Line Analgesic for Most Older Adults

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But there may be a higher stroke risk in elderly patients with diabetes taking the drug
The National Hand Hygiene Initiative has successfully sustained improvement in hand hygiene compliance

National Hand Hygiene Initiative Successful in Australia

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Overall hand hygiene compliance increased from 2009 to 2017; associated drop seen in HA-SAB incidence
Increased screen time in preschool is associated with increased odds of clinically significant externalizing problems and clinically significant inattention problems

Increased Screen Time in Preschool Tied to Worse Inattention

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Odds increased for reporting clinically significant externalizing problems, inattention problems
Increased educational debt appears to directly influence physician practice choice

Loan Forgiveness, Educational Debt May Affect Practice Patterns

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Graduates with loan forgiveness/repayment program more likely to enter primary care fields
In older adults

Stimulation of Targets in Brain May Up Recollection in Seniors

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Effects of stimulation were greater on fMRI recollection signals versus recognition signals
Children with chronic constipation have underlying sensory characteristics that contribute to toileting behavioral difficulties

Sensory Sensitivity Tied to Constipation in Young Children

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Feeding problems due to sensory sensitivities common in children with constipation