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April 2019 Briefing – Neurology

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Here are what the editors at HealthDay consider to be the most important developments in Neurology for April 2019. This roundup includes the latest...
Progress has been made toward developing diagnostic criteria for limbic-predominant age-related TDP-43 encephalopathy

Diagnostic Criteria Proposed for Advanced-Age Proteinopathy

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Gaps remain in understanding of limbic-predominant age-related TDP-43 encephalopathy
For patients with Dravet syndrome and drug-resistant seizures

AAN: Cannabidiol Tied to Drop in Seizures in Dravet Syndrome

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Percentage reduction in convulsive seizures higher for cannabidiol 10 and 20 mg/kg/day versus placebo
Among older adults

Poor Olfaction Tied to Elevated Long-Term Mortality in Seniors

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Correlation evident for those who reported excellent-to-good health at baseline, not fair-to-poor health
The risk for adverse drug reactions may be higher for women

Gender Differences Seen in Adverse Drug Reactions

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Differences found in reaction symptoms and types of drugs tied to adverse reactions
Children with more attention-deficit/hyperactivity disorder (ADHD) symptoms may be at higher risk for an unhealthy diet

Children With ADHD May Have Higher Risk for Poor Diet

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However, having a poor diet does not seem to contribute to ADHD symptom development
Psychostimulant use plays a substantial role in fatal strokes among young adults

Psychostimulant Use Pervasive in Young Adults’ Fatal Strokes

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In cases of hemorrhagic stroke among young adults, psychostimulant use should be considered
Nearly one in five patients referred to a multiple sclerosis specialty center are misdiagnosed

Significant Number of Referred Patients Misdiagnosed With MS

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At MS referral centers, almost one in five new patients have been incorrectly diagnosed with the disease
Naproxen sodium twice daily is not associated with reduced progression of presymptomatic Alzheimer disease among cognitively intact people at risk for the condition

Naproxen Sodium Does Not Slow Presymptomatic Alzheimer Disease

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Study shows increased frequency of adverse events but little impact on rate of change in APS
Patients with recent stroke are rarely screened and treated for osteoporosis

Stroke Patients Infrequently Screened, Treated for Bone Loss

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5.1 percent of patients with stroke, 2.9 percent of those without prior testing had bone mineral density test