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Peripheral nervous system disease is a component of systemic lupus erythematosus disease activity and has a significant negative impact on health-related quality of life

Peripheral Nervous System Events Not Common in Lupus

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History of neuropathy, older age at diagnosis among factors tied to longer time to resolution of PNS events
Cardiorespiratory fitness is positively associated with gray matter volume and total brain volume and with gray matter volume in specific brain areas

Cardiorespiratory Fitness Linked to Gray Matter Volume

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Strong association found for VO2peak with GM volume of left middle temporal gyrus, right hippocampal gyrus
Both recent severe hypoglycemia and lifetime severe hypoglycemia are associated with worse cognition among older adults with type 1 diabetes

Severe Hypoglycemia in Seniors With T1DM May Worsen Cognition

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Findings seen for both recent and lifetime hypoglycemia among older adults with type 1 diabetes
Providing nonsurgical periodontal treatment to patients with type 2 diabetes and periodontitis may significantly reduce tooth loss and diabetes-related microvascular diseases via improved glycemic control

Treating Oral Disease Could Yield T2DM-Related Cost Savings

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Model shows benefits include reductions in tooth loss and diabetes-related microvascular disease
Modestly worse patient experiences are seen following hospital acquisition by another hospital

Patient Experiences Modestly Worse After Hospital Acquisition

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No significant differential changes found in 30-day readmission rates or 30-day mortality
The global intensity of the tau-positron emission tomography signal predicts the rate of subsequent atrophy in patients at early symptomatic Alzheimer disease stages

Tau-PET Signal Predicts Atrophy in Early Alzheimer Disease

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Association between baseline tau-PET and subsequent atrophy particularly strong in younger patients

December 2019 Briefing – Neurology

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Here are what the editors at HealthDay consider to be the most important developments in Neurology for December 2019. This roundup includes the latest...
Autism spectrum disorder is markedly heritable

Severity of Autism Symptoms May Vary in Monozygotic Twins

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Trait correlations for MZ twins differed according to the clinical range of severity for autistic symptoms
Resting-state functional magnetic resonance imaging measures may be able to predict symptoms of attention-deficit/hyperactivity disorder or major depressive disorder in children

fMRI Measures May Predict Psychiatric Symptoms in Children

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Less positive coupling between sgACC, DLPFC at age 7 linked to increase in internalizing behaviors at 11
A machine learning system can generate clinically valid alerts for medication errors that might be missed with existing clinical decision support systems

Machine Learning System Makes More Alerts for Med Errors

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68.2 percent of MedAware alerts would not have been generated with clinical decision support system