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Continuous and intermittent administration of β-lactam antibiotics are similarly efficacious for patients with severe sepsis

Outcomes Equal for Continuous, Intermittent β-Lactams in Sepsis

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No differences in ICU-free days, 90-day survival, organ failure-free days, bacteremia duration
Adverse reactions to St. John's wort are similar to those reported for fluoxetine

Similar Adverse Effects Seen for St. John’s Wort, Fluoxetine

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Majority reported concern females, 26 to 50 years of age
The majority of hospitalists believe that routinely assessing dyspnea severity would enhance their clinical decision making and positively affect patient care

Routine Dyspnea Severity Assessment Could Aid Care

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Regular appraisal in cardiopulmonary disease patients would aid hospitalists' decision making
The 2015 version of the American Board of Internal Medicine maintenance-of-certification program is expected to generate considerable costs

2015 MOC Program Expected to Cost $5.7 Billion Over 10 Years

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Time costs account for 90 percent of maintenance of certification costs, estimated at $5.1 billion
For patients with non-ST-segment elevation acute coronary syndrome

Early Invasive Strategy No Benefit 10 Years After NSTE-ACS

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No improved outcomes versus selective invasive strategy in non-ST segment acute coronary syndrome
The 2008 Hospital-Acquired Conditions Initiative payment changes for pressure ulcers have had a minimal effect

2008 Initiative Had Minimal Impact on Pressure Ulcer Charges

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Hospital-Acquired Conditions Initiative cut payment in 0.003 percent of discharges
From 2002 to 2012

Higher Health Costs for Diabetes Mainly Meds, Inpatient Care

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Individuals with diabetes had more than double the unadjusted mean direct expenditures over 10 years
Not all placebos are equally effective for knee osteoarthritis and some can trigger clinically relevant responses

Not All Placebos Are Equal in Knee Osteoarthritis

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Differential placebo effects can alter estimates of the relative efficacies of active treatments
For Japanese patients who have undergone percutaneous coronary intervention

Atorvastatin/Ezetimibe Beats Atorvastatin After PCI

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Combination therapy linked to greater coronary plaque regression in Japanese patients
Components of the Mediterranean lifestyle may reduce postprandial lipemia

Components of Mediterranean Lifestyle Cut Postprandial Lipemia

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Physical activity shown to reduce PPL, as well as legumes, fish, and herbs, but not wine