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U.S. researchers are challenging a leading theory about the nation's heroin epidemic

Pathway to Heroin Described in NEJM Commentary

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Initial exposure to opioids appears to 'push' potential addicts to heroin
The Affordable Care Act is working as intended

Health Coverage Improved As Result of Affordable Care Act

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Hospital reimbursements up, births among young women more often privately covered
The two-year Ebola outbreak in West Africa that claimed more than 11

WHO: West Africa Ebola Outbreak Is Over

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However, risks remain due to the persistence of the virus in a proportion of survivors
More patients than previously estimated contracted life-threatening infections from contaminated medical scopes in recent years

Scope-Related Infections Higher Than Previously Thought

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U.S. Senate committee recommends FDA assess whether devices require design modifications
A new online tool may help predict whether patients with chronic kidney disease will develop kidney failure in the next two to five years. The report was published in the Jan. 12 issue of the Journal of the American Medical Association.

Online Tool Helps Predict Odds of Kidney Failure in CKD Patients

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New risk calculator estimates who will need dialysis in two to five years
The American Board of Internal Medicine is extending (through the end of 2018) its decision not to require internists to complete various controversial parts of its Maintenance of Certification program in order to keep their certification status

ABIM Extends Decision to Suspend Aspects of MOC Program

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Two-year extension offered for decision not to require internists to complete parts of MOC program
Between 2000 and 2009

Newborn Abstinence Sx Up, Tied to Increasing Prenatal Opioid Use

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~14 to 22 percent of pregnant women in the United States are prescribed opioids
Imatinib (Gleevec) blocks CDK5-mediated peroxisome proliferator-activated receptor γ phosphorylation as an antagonist ligand

PPARγ Antagonist Imatinib Improves Insulin Sensitivity

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Imatinib improves insulin sensitivity without causing side effects seen with other PPARγ-targeting drugs
Use of bone marrow as the stem cell source for hematopoietic stem cell transplantation increases with increasing incomes

Stem Cell Sources Used for HSCT Vary by Country, Resources

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Use of bone marrow most common in Americas, Europe; increases with increasing income
There is variability in radiation-induced breast cancer incidence and mortality associated with digital mammography screening

Incidence of Radiation-Induced Breast Cancer Examined

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Women with large breasts projected to have increased risk of radiation-induced breast cancer