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Outcomes-based pricing for novel and expensive biopharmaceuticals is supported in an Ideas and Opinions piece published online Dec. 13 in the Annals of Internal Medicine.

Outcomes-Based Pricing Suggested for New, Costly Drugs

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Strategy would compel manufacturers and insurers to share accountability for clinical outcomes
A data-driven algorithm for personalized diabetes care can yield substantial improvements in hemoglobin A1c

Data-Driven Algorithm Yields Notable Improvements in HbA1c

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Posttreatment HbA1c lower under algorithm-recommended tx versus standard of care
Liver transplantation patients should undergo addiction consultation to accurately detect alcohol consumption

Addiction Consultation Valuable for Liver Transplant Patients

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Increased alcohol consumption identified in interviews with addiction specialists vs hepatologists
Definitive chemoradiation can potentially cure HIV-associated squamous cell carcinoma of the anal canal

Cetuximab + Chemoradiation Can Cure HIV-Associated Anal Cancer

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Addition of cetuximab may result in less locoregional failure for squamous cell carcinoma of anal canal
Self-care tools can reduce depressive symptoms in patients with age-related macular degeneration or diabetic retinopathy

Self-Care Tools Cut Depression in AMD, Diabetic Retinopathy

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Reduced depressive symptoms in patients with age-related macular degeneration, diabetic retinopathy
A standardized sliding scale insulin (SSI) order sheet can reduce the incidence of SSI-related medication errors

Sliding Scale Insulin Order Sheet Cuts Medication Errors

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Standardized SSI can cut incidence of SSI-related drug errors; doesn't reduce hyper-, hypoglycemia
Staffing the intensive care unit with a communication facilitator is economically feasible

Communication Facilitator in ICU Economically Feasible

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Maximal weekly savings with one full-time facilitator and 15 percent projected ICU mortality
Stroke and atrial fibrillation (AF) recurrence are low one year after AF ablation

Stroke, A-Fib Recurrence Low at One Year After AF Ablation

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No difference in atrial fibrillation recurrence for patients with versus without stroke
The prices of brand-name drugs used by many older Americans rose nearly 130 times faster than inflation last year

AARP: Medication Costs for Seniors Continue to Soar

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Cost of brand-name drugs for chronic conditions rose nearly 130 times faster than inflation rate
For patients who stop oral anticoagulation for a first episode of pulmonary embolism

OSA Is Risk Factor for Recurrent Pulmonary Embolism

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For patients who stop oral anticoagulants for a first episode of PE, OSA is risk factor for recurrence