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Clinical Oral Food Challenges Result in Few Reactions

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86 percent of challenges result in no reactions; anaphylaxis absent in 98 percent
For patients with uncontrolled asthma despite treatment with long-acting beta-agonists and medium-to-high doses of inhaled glucocorticoids

Reduced Asthma Exacerbations Seen With Tezepelumab

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Reduction seen with three dose levels of tezepelumab regardless of blood eosinophil counts
Intensive systolic blood pressure lowering is associated with an increased risk of chronic kidney disease events but a reduced risk of cardiovascular events and mortality

Intensive BP Control Associated With Increased CKD Risk

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However, cardiovascular events, all-cause mortality risk decrease with intensive blood pressure lowering
Digital immunoassays and rapid nucleic acid amplification tests have higher sensitivities for detecting influenza than rapid influenza diagnostic tests

Traditional Flu Tests Not as Accurate as Newer Tests

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Digital immunoassays, rapid nucleic acid amplification tests have better sensitivity
Mailed outreach invitations offering a fecal immunochemical test (FIT) or colonoscopy increase the proportion of participants completing colorectal cancer screening

Mailed Invitations Increase CRC Screening Completion

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And providing specific reminders to general practitioners improves participation in FIT screening
For patients with acute diverticulitis

Acute Diverticulitis Recurrence More Likely With Barium Enema

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Patients who undergo barium enema are more likely to present with higher Hinchey grade at recurrence
Universal sequencing of a broad panel of cancer-related genes is associated with increased detection of potentially clinically significant heritable mutations

Universal Sequencing of Cancer Genes Ups Mutation Detection

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Increased detection of heritable mutations over the predicted yield of testing based on guidelines
Use of evidence-based care processes in routine care for Staphylococcus aureus bacteremia is associated with reduced mortality

Care Process Use Linked to Reduced S. Aureus Mortality

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Use of evidence-based care processes in routine care linked to reduced S. aureus bacteremia mortality
Referring physicians have limited knowledge regarding indications for primary prevention implantable defibrillator use

Knowledge on Primary Prevention ICD Use Found Lacking

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Barriers for referral differ for internists, cardiologists, cardiology residents
A cognitive test involving animal name recall can predict which elderly patients succeed in mastering an insulin self-injection technique within one week

Cognitive Test Predicts Elderly Insulin Injection Success

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Number of animal names recalled in one minute was the most useful indicator