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E-cigarette use changes the profile of innate defense proteins in airway secretions

E-Cigarettes Alter Defense Proteins in Airway Secretions

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Levels of innate defense proteins associated with COPD found to be elevated in e-cigarette users
A combination of clinical factors and payer type increase the likelihood of approval for proprotein convertase subtilisin/kexin type 9 inhibitor treatment

Rate of Approval for PCSK9i Therapy 47 Percent

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Clinical factors and payer type linked to likelihood of approval, with highest approval for Medicare
Overall

More Than One in Five U.S. Working Adults Uses Tobacco

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4.6 percent report current use of two or more products; highest use for construction workers
A significant increase in colorectal lesion frequency is seen at 45 years of age

Colorectal Lesion Frequency Increases at Age 45

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Polyp, adenoma, and neoplasia detection rate higher in 45-49 age group than in younger patients
Diabetes that follows pancreatic disease is frequently classified as type 2 diabetes but is associated with worse glycemic control and higher use of insulin within five years than type 2 diabetes

Diabetes of Exocrine Pancreas Often Classified as T2DM

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Worse glycemic control, more insulin use for diabetes following pancreatic disease than type 2 diabetes
Since 1984

Gastric Cancer Incidence Down, Survival Up

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Incidence declined between 1984 and 2014, but long-term survival rates are still low
For patients undergoing aortic valve replacement

Afternoon Heart Surgery Linked to Better Patient Outcomes

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Lower incidence of major adverse cardiac events for aortic valve replacement surgery in afternoon
Incretin treatment appears to improve non-ST-elevation myocardial infarction outcomes in patients with type 2 diabetes and non-obstructive coronary artery stenosis

Incretin Tied to Better Outcomes in NOCS-Diabetes

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Prognosis for T2DM patients with NSTEMI, coronary artery stenosis improves with incretin
Emergency departments are increasingly a major source of medical care in the United States

ERs Contribute Large Portion of Medical Care Delivery

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Percentage of care delivered by emergency departments increased between 1996 and 2010
For patients with stage I non-small-cell lung cancer

Treatment for Stage I NSCLC Patients Up From 2000 to 2010

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Improved survival for non-small-cell lung cancer patients, driven by better survival in treated patients