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The 99th centile of high-sensitivity cardiac troponin I concentration is substantially higher in a hospital population than the manufacturer's recommended upper limit of normal

Troponin Assay Confusion May Cause Misdiagnosis of Acute MI

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Overall, 5.4 percent of 20,000 patients had high-sensitivity troponin I concentration >40 ng/L
For HIV-infected patients

One-Month Regimen Noninferior for Preventing HIV-Related TB

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One-month rifapentine, isoniazid noninferior to nine months of isoniazid alone
There is considerable concern regarding the potential negative impact that electronic cigarettes and other new products may have on ending all tobacco use and nicotine addiction

E-Cigarettes May Threaten Goal of Achieving Tobacco Endgame

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Concern increasing that use of newer tobacco products may catalyze transition to tobacco products, drugs
Bempedoic acid

Adding Bempedoic Acid to Statin Therapy Reduces LDL Cholesterol

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Genetic variants mimicking effect of ATP citrate lyase inhibitors, statins lower LDL-C in same way
A short regimen is noninferior to a long regimen for patients with rifampin-resistant tuberculosis that is susceptible to fluoroquinolones and aminoglycosides

Short Regimen Noninferior for Rifampin-Resistant Tuberculosis

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Short regimen of nine to 11 months noninferior to 20-month regimen following WHO guidelines
The U.S. Food and Drug Administration will temporarily be overseen by the head of the National Cancer Institute when FDA Commissioner Scott Gottlieb

Head of National Cancer Institute Named Acting FDA Commissioner

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Current commissioner, Scott Gottlieb, will be stepping down in April
More than 2

Mumps Causes Quarantine of Over 2,200 Immigrant Detainees

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25-day quarantine affects facilities in Pine Prairie, Louisiana, and Aurora, Colorado
The U.S. Food and Drug Administration on Tuesday approved a new generic version of the high blood pressure/heart failure drug valsartan

FDA Approves New Generic Valsartan to Ease Shortage

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Certain lots of valsartan recalled due to contamination with trace amounts of nitrosamine
People living in homes with high average air exchange rates are more likely to report chronic cough

Homes With High Ventilation Rates Tied to Respiratory Issues

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High rates of air exchange associated with chronic cough, asthma, asthma-like symptoms
Daily bathing with chlorhexidine plus nasal mupirocin in carriers for methicillin-resistant Staphylococcus aureus does not cut rates of hospital-acquired bacterial infections overall in non-critical care units

Active Bathing in Non-ICU Setting Does Not Cut Infections

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No change seen in risk for hospital-acquired infections overall; benefit seen for those with medical devices