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When empirical antimicrobial therapy is initiated in patients with severe manifestations of sepsis

Initiating Empirical Tx for Sepsis Reduces Blood Culture Sensitivity

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12 percent difference seen in proportion of positive blood cultures before and after antimicrobial therapy
Hospital-level high-risk antibiotic use is associated with the risk for hospital-associated Clostridioides difficile infection

High-Risk Antibiotic Use Linked to Hospital-Associated C. Difficile

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High-risk antibiotic use independently predicts hospital-related Clostridioides difficile infection
Opioid use at three months after an emergency department visit where opioids were prescribed for acute pain is relatively low and not necessarily tied to opioid misuse

Continued Use Low Three Months After ED Opioid Rx for Acute Pain

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Few report using opioids for reason other than pain three months after receiving opioid Rx
Biopsychosocial frailty can predict short-term and longer-term dementia risk

Biopsychosocial Frailty Measure Predicts Risk for Dementia

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Model of physical, psychological, and social elements predicts three- and seven-year dementia risk
High-occupancy hospitals may be sensitive to openings and closures in neighboring emergency departments

ED Openings, Closures May Affect Tx, Outcomes for Acute MI

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ED closures can negatively affect heart attack care at bystander hospitals at near or full capacity
Primary care providers report substantial

Primary Care Faces Challenges in Caring for Kidney Disease

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Lack of knowledge, time, clinical support tools are barriers cited by primary care providers
Initiating donepezil to manage symptoms of Alzheimer disease or other dementias is associated with a higher risk for 30-day admission to the hospital with rhabdomyolysis compared with initiating rivastigmine or galantamine

Donepezil Ups Risk for Hospital Admission for Rhabdomyolysis

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Donepezil linked to increased risk for admission with rhabdomyolysis versus rivastigmine, galantamine
Using his executive powers

New York State to Ban Flavored E-Cigarettes

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Governor says flavored e-cigarettes account for 68 percent of those sold in New York
The measles outbreak that has spread throughout the United States may be winding down as no new cases were reported last week

No New U.S. Measles Cases Reported Last Week

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Measles outbreaks are usually said to be over after 42 days without a new infection
Aspirin for primary prevention of cardiovascular disease is likely to result in net benefit for some patients

Aspirin for Primary Prevention May Offer Net Benefit for Some

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Subgroups with net benefit had higher baseline CVD risk, higher levels of most established CVD risk factors