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Cervicovaginal secretions from pregnant and nonpregnant women contain HIV infectivity-linked immune mediators

Cervicovaginal Secretions Contain HIV-Linked Immune Mediators

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No difference in infectivity for pregnant and nonpregnant women
A case of Kingella kingae keratitis in an HIV-positive adult male is described in a letter to the editor published online Dec. 12 in Clinical & Experimental Ophthalmology.

Kingella kingae Keratitis Described in HIV-Positive Adult

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Patient was 52-year-old HIV-positive male with one week of orthokeratology lens use for myopia
Zika's ability to damage the infant brain may be even more far-reaching and insidious than previously thought

Zika-Related Birth Defects More Extensive Than Thought

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Studies found greater prevalence than believed, more neurological problems appearing months after birth
Specific bacteria may help explain the connection between periodontal disease and rheumatoid arthritis

Bacterial Cause of Periodontal Disease May Drive RA

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Aggregatibacter actinomycetemcomitans implicated in periodontal disease and rheumatoid arthritis
Outcomes-based pricing for novel and expensive biopharmaceuticals is supported in an Ideas and Opinions piece published online Dec. 13 in the Annals of Internal Medicine.

Outcomes-Based Pricing Suggested for New, Costly Drugs

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Strategy would compel manufacturers and insurers to share accountability for clinical outcomes
Definitive chemoradiation can potentially cure HIV-associated squamous cell carcinoma of the anal canal

Cetuximab + Chemoradiation Can Cure HIV-Associated Anal Cancer

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Addition of cetuximab may result in less locoregional failure for squamous cell carcinoma of anal canal
For women with a singleton pregnancy planning a repeat cesarean delivery

Universal Group B Streptococci Screening Not Cost-Effective

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Screening before repeat C-section may become cost-effective in populations with high GBS prevalence
Use of fecal microbiota transplantation is cost-effective for recurrent Clostridium difficile infection

Fecal Microbiota Transplant Cost-Effective for Preventing CDI

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Use of nasoduodenal or colorectal FMT would improve quality of life, cut costs versus vancomycin
Among adults with diagnosed diabetes

CDC Finds Vaccination Coverage Varies for Adults With Diabetes

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Influenza vaccination coverage more prevalent than pneumococcal or hepatitis B vaccination
Colombia is now experiencing a sharp increase in cases of infant microcephaly

CDC: Colombia Sees Increase in Zika-Related Microcephaly

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Research suggests greatest risk for Zika-related microcephaly occurs in the first half of pregnancy