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The United States is stepping up its response to a historic outbreak of Ebola in two African nations. The U.S. Centers for Disease Control and Prevention activated its Emergency Operations Center Thursday to assist in the government's response to the second-largest outbreak of Ebola on record.

CDC Opens Emergency Operations Center for Congo Ebola Outbreak

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The virus has crossed the border from the eastern Democratic Republic of the Congo to Uganda
Seroconversion to human papillomavirus type 16-E6 antibody positivity can occur decades before diagnosis of oropharyngeal squamous cell carcinoma

HPV16 Antibodies Can Develop Long Before Throat Cancer Diagnosis

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HPV16-E6 seropositivity increases with shorter lead time, reaching 38.9 percent for <10 years
For African women seeking effective contraception

HIV Risk Does Not Differ With Three Contraceptive Methods

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No significant difference seen with use of DMPA-IM, copper IUD device, levonorgestrel implant in African women
Low-virulent microorganisms frequently detected on pedicle screws may be an important cause of spinal implant loosening and failure in patients without signs of infection

Microbes Tied to Pedicle Screw Loosening, Spinal Implant Failure

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Low-virulent microorganisms detected using sonication on extracted hardware
Many health care providers in the United Kingdom have little direct experience with online feedback

Most Providers Unaware of Online Feedback About Themselves

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Providers do not encourage patient reviews and often view such feedback as having limited value
Metagenomic next-generation sequencing of cerebrospinal fluid obtained from patients with meningitis or encephalitis can improve diagnosis of neurologic infections

Next-Gen Sequencing of CSF Improves Diagnosis of CNS Infections

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Eight of 13 diagnoses made solely by metagenomic NGS had likely clinical effect, seven guided treatment
Wildlife rabies

CDC: Wildlife Rabies, Especially in Bats, Poses Risk in U.S.

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Seventy percent of rabies infections acquired in the United States attributed to bats
Undervaccinated and unvaccinated children are at increased risk for pertussis

Pertussis Risk Up for Undervaccinated, Unvaccinated Children

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However, most pertussis cases occur among vaccinated children further away from last DTaP dose
Children with community-acquired pneumonia often receive diagnostic testing and antibiotic therapy despite publication of guidelines against their routine use in 2011

Diagnostic Testing, Antibiotics Overused in Pediatric CAP

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Chest radiography ordered in 43 percent, antibiotics prescribed in 73.9 percent of community-acquired pneumonia visits
Nurse understaffing is associated with an increased risk for health care-associated infections among hospitalized patients

Nurse Understaffing Ups Inpatient Infection Risk

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Findings show 15 percent increased risk two days after understaffed day and night shifts